Evidence map›Paper›PMID 25702921›Full record

ArticleBritish journal of clinical pharmacology2015

Potentially inappropriate drug use in older people: a nationwide comparison of different explicit criteria for population-based estimates.

Lucas Morin, Johan Fastbom, Marie-Laure Laroche, Kristina Johnell

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Article in British journal of clinical pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
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30citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Lucas MorinAging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-8486-8610
Johan FastbomAging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Marie-Laure LarocheCentre Hospitalier Universitaire de Limoges, Service de Pharmacologie, Toxicologie et Pharmacovigilance, Limoges, France.
Kristina JohnellAging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim was to investigate the prevalence of potentially inappropriate medication use among older people in Sweden according to five different published sets of explicit criteria from Europe and the US.

methodsThis was a nationwide cross-sectional, register-based study across the whole of Sweden in 2008. All individuals aged 65 years and older were included (n = 1 346 709, both community-dwelling and institutionalized persons). We applied all drug-specific criteria included in the 2012 Beers Criteria, the Laroche's list, the PRISCUS list, the NORGEP criteria and the Swedish National Board of Health and Welfare criteria. The main outcome was the potentially inappropriate drug use according to each set of criteria, separately and combined. Multivariate logistic regression models were used to identify individual factors associated with the use of potentially inappropriate drugs.

resultsThe prevalence of potentially inappropriate medication use varied between the explicit criteria from 16% (NORGEP criteria) to 24% (2012 Beers criteria). Overall, 38% of the older people were exposed to potentially inappropriate drug use by at least one of the five sets of criteria. While controlling for other possible covariates, female gender, institutionalization and polypharmacy were systematically associated with inappropriate drug use, regardless of the set of explicit criteria we considered.

conclusionAlthough explicit criteria for inappropriate drug use among older people have been reported to be quite different in their content, they provide similar measures of the prevalence of potentially inappropriate drug use at the population level.

Indexed as

Population SurveillanceAgedAged, 80 and overCross-Sectional StudiesDrug PrescriptionsFemaleHumansInappropriate PrescribingMalePolypharmacyPrescription DrugsPrevalenceResidence CharacteristicsSwedenPrescription Drugsinappropriate drug usemedicationsolder adultspharmacoepidemiology

Identifiers

PMID25702921
PMCPMC4541979

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.