Evidence map›Paper›PMID 25702795›Full record

ArticleVeterinary and comparative oncology2017

Patient characteristics influencing the variability of distributed parameter-based models in DCE-CT kinetic analysis.

M D La Fontaine, L S McDaniel, L N Kubicek, R J Chappell, L J Forrest, R Jeraj

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary and comparative oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M D La FontaineDepartment of Medical Physics, University of Wisconsin, Madison, WI, USA.
L S McDanielDepartment of Statistics, University of Wisconsin, Madison, WI, USA.
L N KubicekDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.
R J ChappellDepartment of Statistics, University of Wisconsin, Madison, WI, USA.
L J ForrestDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.
R JerajDepartment of Medical Physics, University of Wisconsin, Madison, WI, USA.

Funding

Dose painting based on hypoxia and proliferative responseR01CA136927 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI JERAJ, ROBERT · 2009 to 2013
$1.4M
NCI NIH HHS R01 CA136927
6 · The paper itself

Abstract

Kinetic parameter variability may be sensitive to kinetic model choice, kinetic model implementation or patient-specific effects. The purpose of this study was to assess their impact on the variability of dynamic contrast-enhanced computed tomography (DCE-CT) kinetic parameters. A total of 11 canine patients with sinonasal tumours received high signal-to-noise ratio, test-double retest DCE-CT scans. The variability for three distributed parameter (DP)-based models was assessed by analysis of variance. Mixed-effects modelling evaluated patient-specific effects. Inter-model variability (CV

Indexed as

Analysis of VarianceAnimalsCarcinomaContrast MediaDog DiseasesDogsKineticsParanasal Sinus NeoplasmsSarcomaTomography, X-Ray ComputedContrast MediacanineDCE-CTkinetic analysisperfusion

Identifiers

PMID25702795
PMCPMC6562053

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.