ArticleLangenbeck's archives of surgery2015
Diagnostic value and clinical impact of complementary CT scan prior to surgery for non-localized primary hyperparathyroidism.
Article in Langenbeck's archives of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- The Role of 4D-CT for Pre-Operative Localization in Patients with Primary Hyperparathyroidism with Negative Ultrasonography and/or Sestamibi SPECT/CT.Sisli Etfal Hastanesi tip bulteni · 2023Article
- Assessment of 4DCT imaging findings of parathyroid adenomas in correlation with biochemical and histopathological findings.Japanese journal of radiology · 2022Article
- Detection of parathyroid adenomas with multiphase 4DCT: towards a true four-dimensional technique.BMC medical imaging · 2021Article
- 4DCT Scanning Technique for Primary Hyperparathyroidism: A Scoping Review.Radiology research and practice · 2021Article
- Focused parathyroidectomy for single parathyroid adenoma: a clinical account of 20 patients.Electronic physician · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSuccessful localization is mandatory for focused parathyroidectomy. If ultrasound and sestamibi scan are negative, bilateral neck exploration is necessary. We examined the contribution of complementary computed tomography (CT) scan to identify the affected parathyroid gland.
methodsBetween November 1999 and April 2014, 25 patients (20 females and 5 males; mean age 67 ± 11 years) with negative or dubious standard imaging (ultrasound and sestamibi scan) underwent CT scan prior to parathyroidectomy and were included in this study. Fifteen patients had had previous neck surgery for parathyroidectomy (n = 11) or thyroidectomy (n = 4). Thin-slice CT (n = 9) or four-dimensional (4D) CT imaging (n = 16) was used. Cure was defined as >50 % post-excision fall of intraoperatively measured parathyroid hormone or fall into the normal range, confirmed by normocalcaemia at least 6 months after surgery.
resultsPreoperative CT scan provided correct localization in 13 out of 25 patients (52 %) and was false positive once. Parathyroidectomy was performed by a focused approach in 11 of these 13 patients as well as in 1 patient guided by intraoperatively measured parathyroid hormone (ioPTH). Thirteen patients required bilateral neck exploration. The cure rate was 96 % (24/25 patients). One patient has persistent primary hyperparathyroidism (pHPT) and one a recurrent disease. Six patients presented a multiglandular disease.
conclusionA CT scan identifies about half of abnormal parathyroid glands missed by conventional imaging and allows focused surgery in selected cases.
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