ReviewJournal of feline medicine and surgery2015
DNA mutations of the cat: the good, the bad and the ugly.
Review in Journal of feline medicine and surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 40 citations in OpenAlex.
- Systemic inflammatory biomarkers linked toVeterinary world · 2026Article
- Whole-genome sequencing of CRFK and PG-4 cells to infer the phenotype of the original donor cats.Companion animal health and genetics · 2026Article
- Review
- Chromosome-scale assembly with improved annotation provides insights into breed-wide genomic structure and diversity in domestic cats.Journal of advanced research · 2025Article
- Reproductive Results of Selected Cat Breeds.Life (Basel, Switzerland) · 2025Article
- Shared alleles and genetic structures in different Thai domestic cat breeds: the possible influence of common racial origins.Genomics & informatics · 2024Article
- Different Founding Effects Underlie Dominant Blue Eyes (DBE) in the Domestic Cat.Animals : an open access journal from MDPI · 2024Article
- Selection Signatures Reveal Candidate Genes for the Cornish Rex Breed-Specific Phenotype.Genes · 2024Article
- Classification of feline hypertrophic cardiomyopathy-associated gene variants according to the American College of Medical Genetics and Genomics guidelines.Frontiers in veterinary science · 2024Article
- Reproductive Management in Catteries: Optimising health and wellbeing through veterinarian-breeder collaboration.Journal of feline medicine and surgery · 2022Review
- Web resource on available DNA variant tests for hereditary diseases and genetic predispositions in dogs and cats: An Update.Human genetics · 2021Article
- Patterns of allele frequency differences among domestic cat breeds assessed by a 63K SNP array.PloS one · 2021Article
- A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism.PLoS genetics · 2020Article
- Prevalence ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020Article
- Targeted genotyping by sequencing: a new way to genome profile the cat.Animal genetics · 2019Article
- Escape From X-Chromosome Inactivation: An Evolutionary Perspective.Frontiers in cell and developmental biology · 2019Review
- Applications and efficiencies of the first cat 63K DNA array.Scientific reports · 2018Article
- The practical use of genome sequencing data in the management of a feline colony pedigree.BMC veterinary research · 2017Article
- Precision Medicine in Cats: Novel Niemann-Pick Type C1 Diagnosed by Whole-Genome Sequencing.Journal of veterinary internal medicine · 2017Article
- Mucopolysaccharidosis VI in cats - clarification regarding genetic testing.BMC veterinary research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
practical relevanceThe health of the cat is a complex interaction between its environment (nurture) and its genetics (nature). Over 70 genetic mutations (variants) have been defined in the cat, many involving diseases, structural abnormalities and clinically relevant health concerns. As more of the cat's genome is deciphered, less commonly will the term 'idiopathic' be used regarding the diagnosis of diseases and unique health conditions. State-of-the-art health care will include DNA profiling of the individual cat, and perhaps its tumor, to establish the best treatment approaches. Genetic testing and eventually whole genome sequencing should become routine diagnostics for feline health care. GLOBAL IMPORTANCE: Cat breeds have disseminated around the world. Thus, practitioners should be aware of the breeds common to their region and the mutations found in those regional populations. Specific random-bred populations can also have defined genetic characteristics and mutations. AUDIENCE: This review of 'the good, the bad and the ugly' DNA variants provides the current state of knowledge for genetic testing and genetic health management for cats. It is aimed at feline and general practitioners wanting to update and review the basics of genetics, what tests are available for cats and sources for genetic testing. The tables are intended to be used as references in the clinic. Practitioners with a high proportion of cat breeder clientele will especially benefit from the review. EVIDENCE BASE: The data presented is extracted from peer-reviewed publications pertaining to mutation identification, and relevant articles concerning the heritable trait and/or disease. The author also draws upon personal experience and expertise in feline genetics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.