ArticleBMJ case reports2015
Thrombotic thrombocytopenic purpura as an initial presentation of systemic lupus erythematosus with acquired ADAMTS 13 antibody.
Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Successful Treatment of Refractory Thrombotic Thrombocytopenic Purpura (TTP) With Caplacizumab: A Case Report.Cureus · 2023Article
- Management of acquired, immune thrombocytopenic purpura (iTTP): beyond the acute phase.Therapeutic advances in hematology · 2022Review
- Case Report: Systemic lupus erythematous associated with thrombotic thrombocytopenic purpura, a diagnostic challenge.F1000Research · 2021Article
- An unusual etiology of thrombotic microangiopathy in an adolescent male: Answers.Pediatric nephrology (Berlin, Germany) · 2020Article
- Pancytopenia and TTP-like picture secondary to pernicious anaemia.BMJ case reports · 2020Article
- Systemic Lupus Erythematosus (SLE) with Acute Nephritis, Antineutrophil Cytoplasmic Antibody- (ANCA-) Associated Vasculitis, and Thrombotic Thrombocytopenic Purpura (TTP): A Rare Case Report with Literature Review.Case reports in rheumatology · 2019Article
- A delay in diagnosis: thrombotic thrombocytopenia purpura occurring in systemic lupus erythematous.The Pan African medical journal · 2019Article
- Acquired Thrombotic Thrombocytopenic Purpura in a Patient with Pernicious Anemia.Case reports in hematology · 2017Article
- Pure lupus podocytopathy first presenting as thrombotic thrombocytopenic purpura-like syndrome.Clinical rheumatology · 2016Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a female patient presenting with headache, fatigue, ecchymoses and recent, excessive vaginal bleeding. Prompt review of the peripheral blood smear showed evidence of microangiopathic haemolytic anaemia (MAHA) and thrombocytopenia. Thrombotic thrombocytopenic purpura (TTP) was suspected. Plasma exchange and corticosteroids were started urgently. The patient responded favourably to the treatment. Subsequently, positive serological markers returned and were compatible with systemic lupus erythematosus (SLE). A disintegrin and metalloproteinase with thrombospondin type 1 motifs, member 13 (ADAMTS 13) activity was remarkably low with a positive inhibitory ADAMTS 13 antibody. Mycophenolate and hydroxychloroquine were started along with a prolonged course and taper of corticosteroids. These medications have been maintained with an excellent response in 14 months of follow-up.
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