Evidence map›Paper›PMID 25701573›Full record

ArticleBioinformatics (Oxford, England)2015

Oasis: online analysis of small RNA deep sequencing data.

Vincenzo Capece, Julio C Garcia Vizcaino, Ramon Vidal, Raza-Ur Rahman, Tonatiuh Pena Centeno, Orr Shomroni, Irantzu Suberviola, Andre Fischer, Stefan Bonn

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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  9. MicroRNAs Regulating Autophagy in Neurodegeneration.Advances in experimental medicine and biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vincenzo CapeceLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Julio C Garcia VizcainoLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany Laboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Ramon VidalLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Raza-Ur RahmanLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Tonatiuh Pena CentenoLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Orr ShomroniLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Irantzu SuberviolaLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Andre FischerLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
Stefan BonnLaboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledOasis is a web application that allows for the fast and flexible online analysis of small-RNA-seq (sRNA-seq) data. It was designed for the end user in the lab, providing an easy-to-use web frontend including video tutorials, demo data and best practice step-by-step guidelines on how to analyze sRNA-seq data. Oasis' exclusive selling points are a differential expression module that allows for the multivariate analysis of samples, a classification module for robust biomarker detection and an advanced programming interface that supports the batch submission of jobs. Both modules include the analysis of novel miRNAs, miRNA targets and functional analyses including GO and pathway enrichment. Oasis generates downloadable interactive web reports for easy visualization, exploration and analysis of data on a local system. Finally, Oasis' modular workflow enables for the rapid (re-) analysis of data. AVAILABILITY AND IMPLEMENTATION: Oasis is implemented in Python, R, Java, PHP, C++ and JavaScript. It is freely available at http://oasis.dzne.de. CONTACT: stefan.bonn@dzne.de SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Online SystemsSoftwareComputational BiologyHigh-Throughput Nucleotide SequencingHumansInternetMicroRNAsSequence Analysis, RNAMicroRNAs

Identifiers

PMID25701573
PMCPMC4481843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.