Trial reportAnnals of emergency medicine2015
Color-Coded Prefilled Medication Syringes Decrease Time to Delivery and Dosing Error in Simulated Emergency Department Pediatric Resuscitations.
Trial report in Annals of emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03921346 (A Mobile Device App to Reduce Prehospital Medication Errors and Time to Drug Preparation and Delivery by EMS During Simulated Pediatric Cardiopulmonary Resuscitation), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Mobile Device App to Reduce Prehospital Medication Errors and Time to Drug Preparation and Delivery by EMS During Simulated Pediatric Cardiopulmonary Resuscitation: a Multicenter, Prospective, Randomized, Controlled Trial
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 4. Adult advanced life support.Clinical and experimental emergency medicine · 2026Guideline
- Is there evidence that length-based tapes with precalculated drug doses increase the accuracy of drug dose calculations in children? A systematic review.Clinical and experimental emergency medicine · 2024Pooled it
- Effect of a Mobile App on Medication Errors During Simulated Pediatric Cardiopulmonary Resuscitation: PEDIDOSIS App vs. Conventional Methods. A Multicenter Simulation-based Randomized Controlled Trial.Journal of medical systems · 2026Trial
- Impact of a Mobile App on Paramedics' Perceived and Physiologic Stress Response During Simulated Prehospital Pediatric Cardiopulmonary Resuscitation: Study Nested Within a Multicenter Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- A Mobile Device App to Reduce Time to Drug Delivery and Medication Errors During Simulated Pediatric Cardiopulmonary Resuscitation: A Randomized Controlled Trial.Journal of medical Internet research · 2017Trial
- Development and Validation of Indian Children Length-based Tape (InChiTape) for Use in Critically Sick Children.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Improving Efficiency and Safety with Prefilled Syringes: A Model-Based Economic Evaluation for US Healthcare Settings.ClinicoEconomics and outcomes research : CEOR · 2025Article
- Detecting clinical medication errors with AI enabled wearable cameras.NPJ digital medicine · 2024Article
- Intravenous therapy device labeling in Intensive Care Units: an integrative review.Revista brasileira de enfermagem · 2022Review
- A study of medication errors during the prescription stage in the pediatric critical care services of a secondary-tertiary level public hospital.BMC pediatrics · 2020Article
- Drug dosing errors in simulated paediatric emergencies - Comprehensive dosing guides outperform length-based tapes with precalculated drug doses.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2020Article
- Intubation drug pack containing pre-filled syringes reduces the time to endotracheal intubation in a simulated paediatric emergency.BMJ simulation & technology enhanced learning · 2020Article
- Medication errors during simulated paediatric resuscitations: a prospective, observational human reliability analysis.BMJ open · 2019Observational
- Article
- A systematic review of epinephrine stability and sterility with storage in a syringe.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019Article
- Randomized controlled trials of simulation-based interventions in Emergency Medicine: a methodological review.Internal and emergency medicine · 2018Review
- Accuracy of weight estimation by the Broselow tape is substantially improved by including a visual assessment of body habitus.Pediatric research · 2018Article
- A Mobile Device App to Reduce Medication Errors and Time to Drug Delivery During Pediatric Cardiopulmonary Resuscitation: Study Protocol of a Multicenter Randomized Controlled Crossover Trial.JMIR research protocols · 2017Article
- Part 3. Advanced cardiac life support: 2015 Korean Guidelines for Cardiopulmonary Resuscitation.Clinical and experimental emergency medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
STUDY
objectiveThe Institute of Medicine has called on the US health care system to identify and reduce medical errors. Unfortunately, medication dosing errors remain commonplace and may result in potentially life-threatening outcomes, particularly for pediatric patients when dosing requires weight-based calculations. Novel medication delivery systems that may reduce dosing errors resonate with national health care priorities. Our goal was to evaluate novel, prefilled medication syringes labeled with color-coded volumes corresponding to the weight-based dosing of the Broselow Tape, compared with conventional medication administration, in simulated pediatric emergency department (ED) resuscitation scenarios.
methodsWe performed a prospective, block-randomized, crossover study in which 10 emergency physician and nurse teams managed 2 simulated pediatric arrest scenarios in situ, using either prefilled, color-coded syringes (intervention) or conventional drug administration methods (control). The ED resuscitation room and the intravenous medication port were video recorded during the simulations. Data were extracted from video review by blinded, independent reviewers.
resultsMedian time to delivery of all doses for the conventional and color-coded delivery groups was 47 seconds (95% confidence interval [CI] 40 to 53 seconds) and 19 seconds (95% CI 18 to 20 seconds), respectively (difference=27 seconds; 95% CI 21 to 33 seconds). With the conventional method, 118 doses were administered, with 20 critical dosing errors (17%); with the color-coded method, 123 doses were administered, with 0 critical dosing errors (difference=17%; 95% CI 4% to 30%).
conclusionA novel color-coded, prefilled syringe decreased time to medication administration and significantly reduced critical dosing errors by emergency physician and nurse teams during simulated pediatric ED resuscitations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.