Evidence map›Paper›PMID 25701017›Full record

GuidelineEuropean journal of preventive cardiology2016

European Primary Care Cardiovascular Society (EPCCS) consensus guidance on stroke prevention in atrial fibrillation (SPAF) in primary care.

Fd Richard Hobbs, Clare J Taylor, Geert Jan Geersing, Frans H Rutten, Judith R Brouwer, European Primary Care Cardiovascular Society (EPCCS) SPAF working group

Open access · bronzeAbstract readConsensus StatementPractice GuidelineReview
PubMed Full text at PMC Publisher
In one paragraph

Guideline in European journal of preventive cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Observational
  20. Stroke prevention in atrial fibrillation: we can do better.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Fd Richard HobbsNuffield Department of Primary Care Health Sciences, University of Oxford, UK richard.hobbs@phc.ox.ac.uk.
Clare J TaylorDepartment of Primary Care Clinical Sciences, University of Birmingham, UK.
Geert Jan GeersingJulius Center for Health Sciences and Primary Care, University of Utrecht, the Netherlands.
Frans H RuttenJulius Center for Health Sciences and Primary Care, University of Utrecht, the Netherlands.
Judith R BrouwerMedcon International, Heemstede, the Netherlands.
European Primary Care Cardiovascular Society (EPCCS) SPAF working group
University Medical Center Utrecht · NLUniversity of Birmingham · GBUniversity of Oxford · GB

Funding

Department of Health DRF-2012-05-407Medical Research Council G9900264
6 · The paper itself

Abstract

backgroundAtrial fibrillation affects 1-2% of the general population and 10% of those over 75, and is responsible for around a quarter of all strokes. These strokes are largely preventable by the use of anticoagulation therapy, although many eligible patients are not treated. Recent large clinical trials have added to the evidence base on stroke prevention and international clinical guidelines have been updated.

designConsensus practical recommendations from primary care physicians with an interest in vascular disease and vascular specialists.

methodsA focussed all-day meeting, with presentation of summary evidence under each section of this guidance and review of European guidelines on stroke prevention in atrial fibrillation, was used to generate a draft document, which then underwent three cycles of revision and debate before all panel members agreed with the consensus statements.

resultsSix areas were identified that included how to identify patients with atrial fibrillation, how to determine their stroke risk and whether to recommend modification of this risk, and what management options are available, with practical recommendations on maximising benefit and minimising risk if anticoagulation is recommended and the reasons why antiplatelet therapy is no longer recommended. The summary evidence is presented for each area and simple summary recommendations are highlighted, with areas of remaining uncertainty listed.

conclusionsAtrial fibrillation-related stroke is a major public health priority for most health systems. This practical guidance can assist generalist community physicians to translate the large evidence base for this cause of preventable stroke and implement this at a local level.

Indexed as

AgedAged, 80 and overAnticoagulantsAtrial FibrillationCardiologyConsensusEuropeEvidence-Based MedicineFemaleHemorrhageHumansMaleMiddle AgedPatient SelectionPrimary Health CarePrimary PreventionAnticoagulantsanticoagulationAtrial fibrillationbleeding riskstroke preventionstroke risk

Identifiers

PMID25701017
PMCPMC4766963
OpenAlexW2136059297

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.