ReviewClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2015
Borrelia miyamotoi infection in nature and in humans.
Review in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
130 citing papers in PubMed, 1 synthesis or guideline pooled it, 257 citations in OpenAlex.
- Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review.Parasites & vectors · 2016Pooled it
- Occurrence of Borrelia miyamotoi in Ixodes ricinus and Dermacentor reticulatus ticks removed from human skin in Poland in 2022-2024.Scientific reports · 2026Article
- Tick-Borne Co-Infection in Lyme Disease: Clinical Impact, Diagnostic Challenges, and Therapeutic Perspectives.Microorganisms · 2026Review
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- Article
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- Detection of suitable habitat areas in Japan of the Lyme disease and tick-borne encephalitis vectorsCurrent research in parasitology & vector-borne diseases · 2026Article
- Update on North American tick-borne diseases and how to diagnose them.Journal of clinical microbiology · 2025Review
- Detection of pathogens within Ixodid ticks collected from domestic cats across the USA.Parasites & vectors · 2025Article
- Molecular Typing of Tick-Borne Pathogens in Ixodids of Bosnia and Herzegovina.Microorganisms · 2025Article
- Surveillance of Tick-Borne Pathogens in Ticks from Humans in the Province of Verona, Italy (2018-2022): A Prospective Study.Microorganisms · 2025Article
- Ticks and tick-borne diseases in the northern hemisphere affecting humans.Frontiers in microbiology · 2025Review
- UrinaryJournal of cellular immunology · 2025Article
- The occurrence of Borrelia miyamotoi in Dermacentor reticulatus and Ixodes ricinus ticks in the Chornobyl Exclusion Zone, Ukraine.Scientific reports · 2024Article
- Complete genome sequence ofMicrobiology resource announcements · 2024Article
- Bartonella infections are rare in blood-fed Ixodes scapularis and Ixodes pacificus ticks collected from rodents in the United States.Parasites & vectors · 2024Article
- Combining short- and long-read sequencing unveils geographically structured diversity iniScience · 2024Article
- No evidence of Bartonella infections in host-seeking Ixodes scapularis and Ixodes pacificus ticks in the United States.Parasites & vectors · 2024Article
- Systematic investigation of theOne health (Amsterdam, Netherlands) · 2024Article
- Coinfection ofPathogens (Basel, Switzerland) · 2024Review
70 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Borrelia miyamotoi is a relapsing fever Borrelia group spirochete that is transmitted by the same hard-bodied (ixodid) tick species that transmit the agents of Lyme disease. It was discovered in 1994 in Ixodes persulcatus ticks in Japan. B. miyamotoi species phylogenetically cluster with the relapsing fever group spirochetes, which usually are transmitted by soft-bodied (argasid) ticks or lice. B. miyamotoi infects at least six Ixodes tick species in North America and Eurasia that transmit Lyme disease group spirochetes and may use small rodents and birds as reservoirs. Human cases of B. miyamotoi infection were first reported in 2011 in Russia and subsequently in the United States, Europe and Japan. These reports document the public health importance of B. miyamotoi, as human B. miyamotoi infection appears to be comparable in frequency to babesiosis or human granulocytic anaplasmosis in some areas and may cause severe disease, including meningoencephalitis. The most common clinical manifestations of B. miyamotoi infection are fever, fatigue, headache, chills, myalgia, arthralgia, and nausea. Symptoms of B. miyamotoi infection generally resolve within a week of the start of antibiotic therapy. B. miyamotoi infection should be considered in patients with acute febrile illness who have been exposed to Ixodes ticks in a region where Lyme disease occurs. Because clinical manifestations are nonspecific, etiologic diagnosis requires confirmation by blood smear examination, PCR, antibody assay, in vitro cultivation, and/or isolation by animal inoculation. Antibiotics that have been used effectively include doxycycline for uncomplicated B. miyamotoi infection in adults and ceftriaxone or penicillin G for meningoencephalitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.