ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2015
Sleep disorders in patients with multiple sclerosis.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sleep and cognitive outcomes in multiple sclerosis; a systematic review.BMC psychiatry · 2024Pooled it
- Accelerated long-term forgetting as an objective marker of subjective memory impairment in multiple sclerosis.Neurological research and practice · 2026Article
- Sleep disorders and associated factors in multiple sclerosis patients: a cross-sectional study in Iran.BMC neurology · 2025Article
- Impact of sleep quality on health-related quality of life domains and the mediating effects of symptoms in people with multiple sclerosis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Frequency and risk factors of sleep problems in Egyptian patients with multiple sclerosis.Frontiers in neurology · 2025Article
- Sleep Disorders and Fatigue among Patients with MS: The Role of Depression, Stress, and Anxiety.Neurology research international · 2024Article
- Association of multiple sclerosis with chronic fatigue syndrome, restless legs syndrome, and various sleep disorders, along with the recent updates.Annals of medicine and surgery (2012) · 2023Article
- Volumetric changes in hypothalamic subunits in patients with relapsing remitting multiple sclerosis.Neuroradiology · 2023Article
- Restless leg syndrome in multiple sclerosis: a case-control study.Frontiers in neurology · 2023Article
- Sleep Disturbances, Degree of Disability and the Quality of Life in Multiple Sclerosis Patients.International journal of environmental research and public health · 2022Article
- Hair Cortisol Concentration as a Biomarker of Sleep Quality and Related Disorders.Life (Basel, Switzerland) · 2021Review
- The Effect of Coffee and Caffeine Consumption on Patients with Multiple Sclerosis-Related Fatigue.Nutrients · 2020Article
- Excessive daytime sleepiness and fatigue in neurological disorders.Sleep & breathing = Schlaf & Atmung · 2020Review
- Surveying sleep quality and fatigue in multiple sclerosis patients at a multiple sclerosis center in Kermanshah, Iran, in 2017.Neurobiology of sleep and circadian rhythms · 2020Article
- Impact of depression and fatigue on relapsing remitting multiple sclerosis in Kingdom of Saudi Arabia.Saudi medical journal · 2020Article
- Genetic and Molecular Biology of Multiple Sclerosis Among Iranian Patients: An Overview.Cellular and molecular neurobiology · 2020Review
- Sleep-wake disturbance in patients with brain tumors.Neuro-oncology · 2017Review
- Mobile Technology Use by People Experiencing Multiple Sclerosis Fatigue: Survey Methodology.JMIR mHealth and uHealth · 2017Article
- Sleep-Disordered Breathing in People with Multiple Sclerosis: Prevalence, Pathophysiological Mechanisms, and Disease Consequences.Frontiers in neurology · 2017Review
- Effectiveness of Cognitive Behavioral Therapy on the Quality of Sleep in Women with Multiple Sclerosis: A Randomized Controlled Trial Study.International journal of community based nursing and midwifery · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePoor sleep is a frequent symptom in patients with multiple sclerosis (MS). The objective of the study was to assess the relationship between nocturnal polysomnographic (PSG) findings and quality of sleep, fatigue, and increased daytime sleepiness among patients with MS.
methodsClinical characteristics were collected. Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale (FSS), Epworth Sleepiness Scale (ESS), and International Restless Legs Syndrome Rating Scale were used to assess quality of sleep, fatigue, excessive daytime sleepiness, and the presence of restless legs syndrome (RLS). All patients underwent nocturnal diagnostic PSG examination.
resultsFifty patients with MS were enrolled into the study. Age was the only independent variable significantly determining apnea-hypopnea index and desaturation index (DI) (beta = 0.369, p = 0.010, beta 0.301, p = 0.040). PSQI and ESS score were significantly higher in a population with RLS (p = 0.004, p = 0.011). FSS significantly correlated with DI (r = 0.400, p = 0.048). Presence of RLS was the only independent variable significantly determining PSQI and ESS (p = 0.005, p = 0.025). DI and presence of RLS were independent variables determining FSS (p = 0.015, p = 0.024).
conclusionPresence of RLS seems to be the main factor determining poor sleep, fatigue, and daytime somnolence. Sleep disordered breathing and its severity influences only fatigue in patients with MS.
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