Evidence map›Paper›PMID 25700036›Full record

ArticleCirculation research2015

Higher oily fish consumption in late pregnancy is associated with reduced aortic stiffness in the child at age 9 years.

Jennifer Bryant, Mark Hanson, Charles Peebles, Lucy Davies, Hazel Inskip, Sian Robinson, Philip C Calder, Cyrus Cooper, Keith M Godfrey

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In one paragraph

Article in Circulation research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  11. Intrauterine Growth Restriction: Antenatal and Postnatal Aspects.Clinical medicine insights. Pediatrics · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jennifer BryantFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Mark HansonFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Charles PeeblesFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Lucy DaviesFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Hazel InskipFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Sian RobinsonFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Philip C CalderFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Cyrus CooperFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom.
Keith M GodfreyFrom the NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust (UHSFT) (J.B., M.H., S.R., P.C.C., C.C., K.M.G.), MRC Lifecourse Epidemiology Unit (J.B., L.D., H.I., S.R., C.C., K.M.G.), and Human Development and Health Academic Unit, Faculty of Medicine (M.H., H.I., S.R., P.C.C., C.C., K.M.G.), University of Southampton, Southampton, United Kingdom; and Department of Radiology (J.B., C.P.), UHSFT, Southampton, United Kingdom. kmg@mrc.soton.ac.uk.
NIHR Southampton Biomedical Research Centre · GB

Funding

Arthritis Research UK 17702British Heart Foundation RG/07/009/23120Department of Health SOUDIBRU-2008-1Medical Research Council G0400491Medical Research Council MC_U147574218Medical Research Council MC_U147574222Medical Research Council MC_U147574226Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UP_A620_1017Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Medical Research Council MC_UU_12011/4Medical Research Council MR/J000094/1Versus Arthritis 17702
6 · The paper itself

Abstract

rationaleHigher pulse wave velocity (PWV) reflects increased arterial stiffness and is an established cardiovascular risk marker associated with lower long-chain n-3 polyunsaturated fatty acid intake in adults. Experimentally, maternal fatty acid intake in pregnancy has lasting effects on offspring arterial stiffness.

objectiveTo examine the association between maternal consumption of oily fish, a source of long-chain n-3 polyunsaturated fatty acids, in pregnancy and child's aortic stiffness age 9 years. METHODS AND

resultsIn a mother-offspring study (Southampton Women's Survey), the child's descending aorta PWV was measured at the age of 9 years using velocity-encoded phase-contrast MRI and related to maternal oily fish consumption assessed prospectively during pregnancy. Higher oily fish consumption in late pregnancy was associated with lower childhood aortic PWV (sex-adjusted β=-0.084 m/s per portion per week; 95% confidence interval, -0.137 to -0.031; P=0.002; n=226). Mother's educational attainment was independently associated with child's PWV. PWV was not associated with the child's current oily fish consumption.

conclusionsLevel of maternal oily fish consumption in pregnancy may influence child's large artery development, with potential long-term consequences for later cardiovascular risk.

Indexed as

Pregnancy Trimester, ThirdPrenatal Exposure Delayed EffectsAdultAnimalsBirth WeightBreast FeedingChildEducational StatusFatty Acids, Omega-3Feeding BehaviorFemaleFishesFish OilsFollow-Up StudiesHemodynamicsHumansFatty Acids, Omega-3Fish Oilsfatty acidspregnancyvascular stiffness

Identifiers

PMID25700036
PMCPMC4886834
OpenAlexW2123502783

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.