Evidence map›Paper›PMID 25699562›Full record

ArticleThe American journal of drug and alcohol abuse2015

Does the Transmissible Liability Index (TLI) assessed in late childhood predict suicidal symptoms at young adulthood?

Jack R Cornelius, Levent Kirisci, Maureen Reynolds, Michael Vanyukov, Ralph Tarter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of drug and alcohol abuse, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jack R CorneliusCenter for Education and Drug Abuse Research (CEDAR), University of Pittsburgh , Pittsburgh, PA , USA.
Levent Kirisci
Maureen Reynolds
Michael Vanyukov
Ralph Tarter
University of Pittsburgh · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
TRANSLATION MODULEP50DA005605 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RIDENOUR, TY A · 1989 to 2014
$25.7M
Alcohol and Substance Use Disorders from Adolescence through Age 30R01AA013397 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARTIN, CHRISTOPHER S · 2002 to 2012
$3.9M
Social Network Influences on Adolescent AUD Treatment OutcomesR01AA014357 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHUNG, TAMMY · 2004 to 2013
$3.5M
Fluoxetine for MDD/Cannabis Disorder in Young PeopleR01DA019142 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CORNELIUS, JACK R · 2004 to 2009
$2.6M
Pharmacological Intervention ProjectR01AA013370 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CORNELIUS, JACK R · 2001 to 2005
$2.0M
Drug Addiction Transitions from Adolesence to AdulthoodR01DA014635 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CLARK, DUNCAN B. · 2001 to 2005
$1.8M
FLUOXETINE-TREATED AUD-MDD TEENS: LONG TERM OUTCOMESR01AA015173 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CORNELIUS, JACK R · 2005 to 2009
$1.6M
Quantifying and Tracking Risk for Substance Use DisorderK02DA017822 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KIRISCI, LEVENT · 2005 to 2014
$1.3M
ADOLESCENT PSYCHOPATHOLOGY AND ALCOHOL USE DISORDERSK02AA000291 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CLARK, DUNCAN B. · 1999 to 2008
$1.1M
Longitudinal Modeling of SUD EtiologyK05DA031248 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TARTER, RALPH E · 2012 to 2016
$679k
Psychopathology in Pharmacotherapy of AUD/MDD TeensK24AA015320 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CORNELIUS, JACK R · 2005 to 2009
$575k
NCATS NIH HHS UL1 TR000005NIAAA NIH HHS K02 AA000291NIAAA NIH HHS K02 AA018195NIAAA NIH HHS K24 AA015320NIAAA NIH HHS K24 AA15320NIAAA NIH HHS R01 AA013370NIAAA NIH HHS R01 AA013397NIAAA NIH HHS R01 AA014357NIAAA NIH HHS R01 AA015173NIAAA NIH HHS R01 AA13397NIAAA NIH HHS R01 AA14357NIAAA NIH HHS R21 AA022123NIAAA NIH HHS R21 AA022863NIDA NIH HHS K02 DA017822NIDA NIH HHS K05 DA031248NIDA NIH HHS P50 DA005605NIDA NIH HHS R01 DA014635NIDA NIH HHS R01 DA019142NIDA NIH HHS R01 DA14635
6 · The paper itself

Abstract

objectiveOur previous work demonstrated that the Transmissible Liability Index (TLI), an instrument designed as an index of liability for substance use disorder (SUD), is associated with risk of substance use disorder. This longitudinal study assessed whether TLI measured in 10-12-year-olds (late childhood) predicts suicidal behavior from age 12-14 (preadolescence) to age 25 (young adulthood). We hypothesized that TLI would predict number and severity of suicide attempts.

methodsSubjects were sons of men who had lifetime history of SUD (n = 250), called the High Average Risk (HAR) group, and sons of men with no lifetime history of a SUD (n = 250), called the Low Average Risk (LAR) group. The TLI was delineated at baseline (age 10-12), and age-specific versions were administered at 12-14, 16, 19, 22, and 25 years of age.

resultsTLI was significantly associated with number and severity of lifetime suicide attempts.

conclusionsThese findings confirm the hypothesis that TLI assessed at late childhood is a predictor of frequency and severity of suicidal behavior from preadolescence to young adulthood.

Indexed as

Suicidal IdeationAdolescentAdultChildHumansLongitudinal StudiesMaleRisk FactorsSuicide, AttemptedYoung AdultsuicideTransmissible Liability Index (TLI)young adults

Identifiers

PMID25699562
PMCPMC4435565
OpenAlexW2065471029

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.