ArticlePLoS neglected tropical diseases2015
High prevalence of Tropheryma whipplei in Lao kindergarten children.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Rare but Critical: SevereClinical case reports · 2026Article
- A case of pulmonary nodular lesion caused by Tropheryma whipplei infection: a case report and literature review.BMC pulmonary medicine · 2025Review
- ExploringFrontiers in pharmacology · 2025Article
- Prevalence estimation of Tropheryma whipplei in duodenal biopsy tissues of Koreans.Annals of clinical microbiology and antimicrobials · 2024Article
- Prevalence and detection of Tropheryma whipplei in the stools of Korean patients with diarrhea using real-time PCRs.Annals of clinical microbiology and antimicrobials · 2022Article
- Tropheryma whipplei Intestinal Colonization in Migrant Children, Greece.Emerging infectious diseases · 2022Article
- Article
- Tropheryma whipplei in the stool samples of children with acute diarrhea: a study from Tehran, Iran.BMC infectious diseases · 2022Article
- Seasonal Patterns of Enteric Pathogens in Colombian Indigenous People-A More Pronounced Effect on Bacteria Than on Parasites.Pathogens (Basel, Switzerland) · 2022Article
- Article
- Intestinal Colonization withMicroorganisms · 2021Article
- Tropheryma whipplei in Feces of Patients with Diarrhea in 3 Locations on Different Continents.Emerging infectious diseases · 2021Article
- Clinical manifestations of Whipple's disease mimicking rheumatic disorders.Reumatologia · 2021Review
- Whipple's Disease: A Well-Done Outcome to a Rare Disease.Digestive diseases and sciences · 2019Article
- Clinical Manifestations, Treatment, and Diagnosis of Tropheryma whipplei Infections.Clinical microbiology reviews · 2017Review
- Tropheryma whipplei as a Cause of Epidemic Fever, Senegal, 2010-2012.Emerging infectious diseases · 2016Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundTropheryma whipplei is a bacterium commonly found in feces of young children in Africa, but with no data from Asia. We estimated the prevalence of T. whipplei carriage in feces of children in Lao PDR (Laos). METHODS/PRINCIPAL
findingsUsing specific quantitative real-time PCR, followed by genotyping for each positive specimen, we estimated the prevalence of T. whipplei in 113 feces from 106 children in Vientiane, the Lao PDR (Laos). T. whipplei was detected in 48% (51/106) of children. Those aged ≤ 4 years were significantly less frequently positive (17/52, 33%) than older children (34/54, 63%; p< 0.001). Positive samples were genotyped. Eight genotypes were detected including 7 specific to Laos. Genotype 2, previously detected in Europe, was circulating (21% of positive children) in 2 kindergartens (Chompet and Akad). Genotypes 136 and 138 were specific to Chompet (21% and 15.8%, respectively) whereas genotype 139 was specific to Akad (10.55%). CONCLUSIONS/SIGNIFICANCE: T. whipplei is a widely distributed bacterium, highly prevalent in feces of healthy children in Laos. Further research is needed to identify the public health significance of this finding.
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