ArticleNursing and midwifery studies2014
Investigating the effect of zinc chloride to control external bleeding in rats.
Article in Nursing and midwifery studies, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- The Advantages and Disadvantages of Methods Used to Control Liver Bleeding: A Review.Trauma monthly · 2015Review
- Efficacy and safety of aluminum chloride in controlling external hemorrhage: an animal model study.Iranian Red Crescent medical journal · 2015Article
- Use of ferric sulfate to control hepatic bleeding.Trauma monthly · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite all progresses in surgical science, bleeding caused by traffic accidents is still a challenge for surgeons to save patients' lives. Therefore, introducing an effective method to control external bleeding is an important research priority.
objectivesThis study aimed to compare haemostatic effect of zinc chloride and simple suturing to control external bleeding. MATERIALS AND
methodsIn this animal model study, 60 male Wistar rats were used. An incision (two cm in length and half a cm in depth) was made on shaved back of rats. The hemostasis time was measured once using zinc chloride with different concentrations (5%, 10%, 15%, 25%, and 50%) and then using simple suturing. Skin tissue was assessed for pathological changes. Due to abnormal distribution of variables in Kolmogorov-Smirnov test, the data was analyzed using Kruskal-Wallis test Mann-Whitney U tests.
resultsIn all the groups, complete hemostasis occurred. Hemostasis times of different concentrations of zinc chloride were significantly less than that of the control group (P < 0.001).
conclusionsZinc chloride was effective to control external bleeding in rats.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.