Evidence map›Paper›PMID 25699246›Full record

ArticleFrontiers in public health2015

Evaluation of the Effectiveness of a Novel Brain and Vestibular Rehabilitation Treatment Modality in PTSD Patients Who have Suffered Combat-Related Traumatic Brain Injuries.

Frederick R Carrick, Kate McLellan, J Brandon Brock, Cagan Randall, Elena Oggero

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02003352 (Evaluation of the Effectiveness of a Novel Brain and Vestibular Rehabilitation Treatment Modality in PTSD Patients Who Have Suffered Combat Related Traumatic Brain Injuries), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02003352 nacompletednot on this map

Evaluation of the Effectiveness of a Novel Brain and Vestibular Rehabilitation Treatment Modality in PTSD Patients Who Have Suffered Combat Related Traumatic Brain Injuries

TypeinterventionalSponsorCarrick Institute for Graduate StudiesRan2014 to 2014Enrolled98ConditionsPTSD, TBIArmsFunctional Neurological Rehabilitation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Establishment and evaluation of anFrontiers in public health · 2022
    Trial
  3. Article
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Frederick R CarrickNeurology, Carrick Brain Centers , Dallas, TX , USA ; Neurology, Carrick Institute , Cape Canaveral, FL , USA ; Harvard Medical School Global Clinical Scholars Research Training (GCSRT) , Boston, MA , USA.
Kate McLellanNeurology, Carrick Brain Centers , Dallas, TX , USA ; Neurology, Carrick Institute , Cape Canaveral, FL , USA.
J Brandon BrockNeurology, Carrick Brain Centers , Dallas, TX , USA ; Neurology, Carrick Institute , Cape Canaveral, FL , USA.
Cagan RandallNeurology, Carrick Brain Centers , Dallas, TX , USA.
Elena OggeroNeurology, Carrick Institute , Cape Canaveral, FL , USA ; Electrical and Computer Engineering Department, University of Wyoming , Laramie, WY , USA.
Carrick Institute · USHarvard University · USUniversity of Wyoming · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBlast-related head injuries are among the most prevalent injuries suffered by military personnel deployed in combat and mild traumatic brain injury (mTBI) or concussion on the battlefield in Iraq/Afghanistan has resulted in its designation as a "signature injury." Vestibular complaints are the most frequent sequelae of mTBI, and vestibular rehabilitation (VR) has been established as the most important treatment modality for this group of patients. MATERIALS AND

methodsWe studied the effectiveness of a novel brain and VR treatment post-traumatic stress disorder (PTSD) in subjects who had suffered combat-related traumatic brain injuries in terms of PTSD symptom reduction. The trial was registered as ClinicalTrials.gov Identifier: NCT02003352. (http://clinicaltrials.gov/ct2/show/NCT02003352?term=carrick&rank=6). We analyzed the difference in the Clinician Administered DSM-IV PTSD Scale (CAPS) scores pre- and post-treatment using our subjects as their own matched controls. The study population consisted of 98 combat veterans maintaining an alpha of <0.05 and power of 80%.

resultsPrior to treatment, 75 subjects representing 76.53 % of the sample were classified in the 2 most severe categories of PTSD. Forty-one subjects, representing 41.80 % of the total sample, were classified in the extreme category of PTSD and 34 subjects, representing 34.70 % of the total sample, were classified in the severe category of PTSD. After treatment, we observed a large reduction in CAPS severity scores with both statistical and substantive significance. DISCUSSION: Treatment of PTSD as a physical injury rather than a psychiatric disorder is associated with strong statistical and substantive significant outcomes associated with a decrease of PTSD classification. The stigma associated with neuropsychiatric disorders may be lessened when PTSD is treated with brain and VR with a potential decrease in suffering of patients, family, and society.

Indexed as

brainDSM-IV CAPSoff vertical axis rotationPTSDvestibular rehabilitation

Identifiers

PMID25699246
PMCPMC4316606
OpenAlexW2153451900

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.