Evidence map›Paper›PMID 25699242›Full record

ReviewFrontiers in cellular and infection microbiology2015

Biofilm formation by Streptococcus agalactiae: influence of environmental conditions and implicated virulence factors.

Roberto Rosini, Immaculada Margarit

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 128 citations in OpenAlex.

  1. Antibacterial Activity of Rosmarinic Acid AgainstAnimals : an open access journal from MDPI · 2026
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  11. A CRISPRi library screen in group BInfection and immunity · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Frontiers in veterinary science · 2025
    Article
  16. Article
  17. A CRISPRi Library Screen in Group BbioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Roberto RosiniNovartis Vaccines Siena, Italy.
Immaculada MargaritNovartis Vaccines Siena, Italy.
Novartis (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcus agalactiae (Group B Streptococcus, GBS) is an important human pathogen that colonizes the urogenital and/or the lower gastro-intestinal tract of up to 40% of healthy women of reproductive age and is a leading cause of sepsis and meningitis in the neonates. GBS can also infect the elderly and immuno-compromised adults, and is responsible for mastitis in bovines. Like other Gram-positive bacteria, GBS can form biofilm-like three-dimensional structures that could enhance its ability to colonize and persist in the host. Biofilm formation by GBS has been investigated in vitro and appears tightly controlled by environmental conditions. Several adhesins have been shown to play a role in the formation of GBS biofilm-like structures, among which are the protein components of pili protruding outside the bacterial surface. Remarkably, antibodies directed against pilus proteins can prevent the formation of biofilms. The implications of biofilm formation in the context of GBS asymptomatic colonization and dissemination to cause invasive disease remain to be investigated in detail.

Indexed as

BiofilmsBacterial ProteinsHumansStreptococcal InfectionsStreptococcus agalactiaeVirulence FactorsBacterial ProteinsVirulence Factorsbiofilmsgroup B streptococcuspili/fimbriae/curlistreptococcal infectionsStreptococcus agalactiae

Identifiers

PMID25699242
PMCPMC4316791
OpenAlexW2044977887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.