ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2015
Diversity of human papillomavirus in the anal canal of men: the HIM Study.
Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Visual clues - dermatological manifestations of sexually transmitted infections in men.Nature reviews. Urology · 2026Review
- Article
- The genetic diversity of human papillomavirus types from the species Gammapapillomavirus 15: HPV135, HPV146, and HPV179.PloS one · 2021Article
- Assessing Gammapapillomavirus infections of mucosal epithelia with two broad-spectrum PCR protocols.BMC infectious diseases · 2020Article
- Cervical, anal and oral HPV detection and HPV type concordance among women referred for colposcopy.Infectious agents and cancer · 2020Article
- Discovery, characterisation and genomic variation of six novel Gammapapillomavirus types from penile swabs in South Africa.Papillomavirus research (Amsterdam, Netherlands) · 2019Article
- Epidemiology and biology of cutaneous human papillomavirus.Clinics (Sao Paulo, Brazil) · 2018Review
- Prevalence and correlates of beta human papillomavirus detection in fingernail samples from mid-adult women.Papillomavirus research (Amsterdam, Netherlands) · 2018Article
- Beta and gamma human papillomaviruses in anal and genital sites among men: prevalence and determinants.Scientific reports · 2018Article
- Concordance of Beta-papillomavirus across anogenital and oral anatomic sites of men: The HIM Study.Virology · 2017Article
- Cervical Infection with Cutaneous Beta and Mucosal Alpha Papillomaviruses.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017Article
- Prevalence of cutaneous beta and gamma human papillomaviruses in the anal canal of men who have sex with women.Papillomavirus research (Amsterdam, Netherlands) · 2017Article
- Diversity of beta-papillomavirus at anogenital and oral anatomic sites of men: The HIM Study.Virology · 2016Article
- Identification of a novel human papillomavirus by metagenomic analysis of vaginal swab samples from pregnant women.Virology journal · 2016Article
- Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
Abstract
Human papillomavirus (HPV) infections are associated with the development of anogenital lesions in men. There are no reports describing the distribution of non-α HPV types in the anal canal of a sexually diverse group of men. The HPV Infection in Men (HIM) Study is a multicentre study on the natural history of HPV infection in Brazil, Mexico, and the USA. At baseline, 12% of anal canal PCR HPV-positive specimens were not typed by the Roche Linear Array, and were considered to be unclassified. Our goals were to characterize HPVs among these unclassified specimens at baseline, and to assess associations with participant socio-demographic and behavioural characteristics. Unclassified HPVs were typed by sequencing of amplified PGMY09/11 products or cloning of PGMY/GP + nested amplicons followed by sequencing. Further analysis was conducted with FAP primers. Of men with unclassified HPV in the anal canal, most (89.1%) were men who have sex with women. Readable sequences were produced for 62.8% of unclassified specimens, of which 75.2% were characterized HPV types. Eighteen, 26 and three different α-HPV, β-HPV and γ-HPV types were detected, respectively. α-HPVs were more commonly detected among young men (18-30 years) than among older men (45-70 years), whereas β-HPVs were more frequent among mid-adult men (31-44 years). β-HPVs were more common among heterosexual men (85.0%) than among non-heterosexual men. All β-HPVs detected among non-heterosexual men were β2-HPV types. The high prevalence of β-HPV in the anal canal of men who do not report receptive anal sex is suggestive of other forms of transmission that do not involve penile-anal intercourse.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.