Evidence map›Paper›PMID 25698624›Full record

ArticleAJNR. American journal of neuroradiology2015

Fast contrast-enhanced 4D MRA and 4D flow MRI using constrained reconstruction (HYPRFlow): potential applications for brain arteriovenous malformations.

W Chang, Y Wu, K Johnson, M Loecher, O Wieben, M Edjlali, C Oppenheim, P Roca, J Hald, B Aagaard-Kienitz and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Brain arteriovenous malformation flow after stereotactic radiosurgery: Role of quantitative MRA.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

W ChangFrom the Department of Radiology (W.C.), University of California, Los Angeles, Los Angeles, California.
Y WuMedical Physics (Y.W., K.J., M.L., O.W., C.M.), University of Wisconsin School of Medicine, Madison, Wisconsin.
K JohnsonMedical Physics (Y.W., K.J., M.L., O.W., C.M.), University of Wisconsin School of Medicine, Madison, Wisconsin.
M LoecherMedical Physics (Y.W., K.J., M.L., O.W., C.M.), University of Wisconsin School of Medicine, Madison, Wisconsin.
O WiebenMedical Physics (Y.W., K.J., M.L., O.W., C.M.), University of Wisconsin School of Medicine, Madison, Wisconsin.
M EdjlaliDepartment of Radiology (M.E., C.O., P.R.), Université Paris-Descartes, Paris, France.
C OppenheimDepartment of Radiology (M.E., C.O., P.R.), Université Paris-Descartes, Paris, France.
P RocaDepartment of Radiology (M.E., C.O., P.R.), Université Paris-Descartes, Paris, France.
J HaldDepartment of Radiology (J.H.), Rikshospitalet, Oslo, Norway.
B Aagaard-KienitzDepartments of Radiology (B.A.-K., P.T.).
D NiemannNeurosurgery (D.N.).
C MistrettaMedical Physics (Y.W., K.J., M.L., O.W., C.M.), University of Wisconsin School of Medicine, Madison, Wisconsin.
P TurskiDepartments of Radiology (B.A.-K., P.T.) pturski@uwhealth.org.

Funding

Accelerated Neuro-MRA Using Compressed Sensing and Constrained ReconstructionR01NS066982 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, KEVIN MICHAEL, TURSKI, PATRICK ALAN · 2010 to 2018
$2.7M
NINDS NIH HHS R01 NS066982
6 · The paper itself

Abstract

background and purposeHYPRFlow is a novel imaging strategy that provides fast, high-resolution contrast-enhanced time-resolved images and measurement of the velocity of the entire cerebrovascular system. Our hypothesis was that the images obtained with this strategy are of adequate diagnostic image quality to delineate the major components of AVMs. MATERIALS AND

methodsHYPRFlow and 3D TOF scans were obtained in 21 patients with AVMs with correlative DSA examinations in 14 patients. The examinations were scored for image quality and graded by using the Spetzler-Martin criteria. Mean arterial transit time and overlap integrals were calculated from the dynamic image data. Volume flow rates in normal arteries and AVM feeding arteries were measured from the phase contrast data.

resultsHYPRFlow was equivalent to 3D-TOF in delineating normal arterial anatomy, arterial feeders, and nidus size and was concordant with DSA for AVM grading and venous drainage in 13 of the 14 examinations. Mean arterial transit time on the AVM side was 0.49 seconds, and on the normal contralateral side, 2.53 seconds with P < .001. Across all 21 subjects, the mean arterial volume flow rate in the M1 segment ipsilateral to the AVM was 4.07 ± 3.04 mL/s; on the contralateral M1 segment, it was 2.09 ± 0.64 mL/s. The mean volume flow rate in the largest feeding artery to the AVM was 3.86 ± 2.74 mL/s.

conclusionsHYPRFlow provides an alternative approach to the MRA evaluation of AVMs, with the advantages of increased coverage, 0.75-second temporal resolution, 0.68-mm isotropic spatial resolution, and quantitative measurement of flow in 6 minutes.

Indexed as

AdultAgedAngiography, Digital SubtractionFemaleHumansIntracranial Arteriovenous MalformationsMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleNeuroimaging

Identifiers

PMID25698624
PMCPMC6278607

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.