Evidence map›Paper›PMID 25698236›Full record

ReviewJournal of biomechanics2015

Toward patient-specific articular contact mechanics.

Gerard A Ateshian, Corinne R Henak, Jeffrey A Weiss

Abstract readReview
In one paragraph

Review in Journal of biomechanics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Clinical significance and mechanism of LncRNA GAS-5 in osteoarthritis.American journal of translational research · 2021
    Article
  8. Integration of Three-dimensional Technologies in Orthopedics: A Tool for Preoperative Planning of Tibial Plateau Fractures.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Assessment of cartilage contact pressure and loading in the hip joint during split posture.International journal of computer assisted radiology and surgery · 2016
    Article
  15. Article
  16. Osteoarthritis year in review 2015: mechanics.Osteoarthritis and cartilage · 2016
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gerard A AteshianDepartment of Mechanical Engineering, Columbia University, New York, NY 10027, USA.
Corinne R HenakDepartment of Biomedical Engineering, Cornell University, Ithaca, NY 14850, USA.
Jeffrey A WeissDepartment of Bioengineering, Department of Orthopaedics, and Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USA.

Funding

Finite Elements For Biomechanics And BiophysicsR01GM083925 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI GERARD A. ATESHIAN, JEFFREY A. WEISS · 2008 to 2026
$7.6M
BIOTRIBOLOGY OF DIARTHRODIAL JOINTSR01AR043628 · NIAMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI ATESHIAN, GERARD A. · 2000 to 2013
$3.1M
Biomechanics of the Dysplastic HipR01AR053344 · NIAMS · UNIVERSITY OF UTAH · PI WEISS, JEFFREY A. · 2007 to 2011
$1.3M
NIAMS NIH HHS R01 AR043628NIAMS NIH HHS R01AR043628NIAMS NIH HHS R01 AR053344NIAMS NIH HHS R01AR053344NIGMS NIH HHS R01 GM083925NIGMS NIH HHS R01GM083925
6 · The paper itself

Abstract

The mechanics of contacting cartilage layers is fundamentally important to understanding the development, homeostasis and pathology of diarthrodial joints. Because of the highly nonlinear nature of both the materials and the contact problem itself, numerical methods such as the finite element method are typically incorporated to obtain solutions. Over the course of five decades, we have moved from an initial qualitative understanding of articular cartilage material behavior to the ability to perform complex, three-dimensional contact analysis, including multiphasic material representations. This history includes the development of analytical and computational contact analysis methods that now provide the ability to perform highly nonlinear analyses. Numerical implementations of contact analysis based on the finite element method are rapidly advancing and will soon enable patient-specific analysis of joint contact mechanics using models based on medical image data. In addition to contact stress on the articular surfaces, these techniques can predict variations in strain and strain through the cartilage layers, providing the basis to predict damage and failure. This opens up exciting areas for future research and application to patient-specific diagnosis and treatment planning applied to a variety of pathologies that affect joint function and cartilage homeostasis.

Indexed as

Patient-Specific ModelingCartilage, ArticularHumansJoints

Identifiers

PMID25698236
PMCPMC4416416

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.