ArticleBrain stimulation
Cross-hemispheric Alternating Current Stimulation During a Nap Disrupts Slow Wave Activity and Associated Memory Consolidation.
Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- The Effects of Transcranial Electrical Stimulation of the Brain on Sleep: A Systematic Review.Frontiers in psychiatry · 2021Pooled it
- Triangular Wave tACS Improves Working Memory Performance by Enhancing Brain Activity in the Early Stage of Encoding.Neuroscience bulletin · 2025Trial
- Low frequency transcranial electrical stimulation does not entrain sleep rhythms measured by human intracranial recordings.Nature communications · 2017Trial
- From Therapeutic Heterogeneity to Precision Neuromodulation: Non-Invasive Brain Stimulation for Chronic Insomnia.Nature and science of sleep · 2026Review
- What can neurofeedback and transcranial alternating current stimulation reveal about cross-frequency coupling?Frontiers in neuroscience · 2025Article
- Temporal dynamics of negative emotional memory reprocessing during sleep.Translational psychiatry · 2024Article
- Differential online and offline effects of theta-tACS on memory encoding and retrieval.Cognitive, affective & behavioral neuroscience · 2024Article
- Theta EEG neurofeedback promotes early consolidation of real life-like episodic memory.Cognitive, affective & behavioral neuroscience · 2023Article
- Item-specific neural representations during human sleep support long-term memory.PLoS biology · 2023Article
- Gamma neuromodulation improves episodic memory and its associated network in amnestic mild cognitive impairment: a pilot study.Neurobiology of aging · 2023Article
- Closed-Loop tACS Delivered during Slow-Wave Sleep Reduces Retroactive Interference on a Paired-Associates Learning Task.Brain sciences · 2023Article
- Neurocognitive, physiological, and biophysical effects of transcranial alternating current stimulation.Trends in cognitive sciences · 2023Review
- Effects of Transcranial Alternating Current Stimulation and Neurofeedback on Alpha (EEG) Dynamics: A Review.Frontiers in human neuroscience · 2021Review
- A Comparison of Closed Loop vs. Fixed Frequency tACS on Modulating Brain Oscillations and Visual Detection.Frontiers in human neuroscience · 2021Article
- Targeting sleep oscillations to improve memory in schizophrenia.Schizophrenia research · 2020Review
- Neuromodulation of sleep rhythms in schizophrenia: Towards the rational design of non-invasive brain stimulation.Schizophrenia research · 2020Review
- Longitudinal Association Between Sleep Duration and Depressive Symptoms in Chinese Elderly.Nature and science of sleep · 2020Article
- Transient Amplitude Modulation of Alpha-Band Oscillations by Short-Time Intermittent Closed-Loop tACS.Frontiers in human neuroscience · 2020Article
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Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundSlow Wave Activity (SWA), the low frequency (<4 Hz) oscillations that characterize Slow Wave Sleep (SWS) are thought to relate causally to declarative memory consolidation during nocturnal sleep. Evidence is conflicting relating SWA to memory consolidation during nap however. OBJECTIVE/HYPOTHESIS: We applied transcranial alternating current stimulation (tACS) - which, with a cross-hemispheric electrode montage (F3 and F4 - International 10:20 EEG system), is able to disrupt brain oscillations-to determine if disruption of low frequency oscillation generation during afternoon nap is causally related to disruption in declarative memory consolidation.
methodsEight human subjects each participated in stimulation and sham nap sessions. A verbal paired associate learning (PAL) task measured memory changes. During each nap period, five 5-min stimulation (0.75 Hz cross-hemispheric frontal tACS) or sham intervals were applied with 1-min post-stimulation intervals (PSI's). Spectral EEG power for Slow (0.7-0.8 Hz), Delta (1.0-4.0 Hz), Theta (4.0-8.0 Hz), Alpha (8.0-12.0 Hz), and Spindle-range (12.0-14.0) frequencies was analyzed during the 1-min preceding the onset of stimulation and the 1-min PSI's.
resultsAs hypothesized, power reduction due to stimulation positively correlated with reduction in word-pair recall post-nap specifically for Slow (P < 0.0022) and Delta (P < 0.037) frequency bands.
conclusionsThese results provide preliminary evidence suggesting a causal and specific role of SWA in declarative memory consolidation during nap.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.