ArticleVirchows Archiv : an international journal of pathology2015
Clinicopathological characteristics of urothelial bladder cancer in patients less than 40 years old.
Article in Virchows Archiv : an international journal of pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04811846 (Circulating Tumor Cell), which is not on this map. Cited by 105 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Circulating Tumor Cell (CTC) Quantification During Transurethral Resection (TURBT) and Plasma Kinetic Vaporisation (PKVBT) of Transitional Cell Carcinoma in Purging Fluid and Blood: a Randomized Controlled Trial
Who cites it
105 citing papers in PubMed, 4 syntheses or guidelines pooled it, 221 citations in OpenAlex.
- Sex-specific differences in recurrence and progression following cytostatic intravesical chemotherapy for non-muscle invasive urothelial bladder cancer (NMIBC).Journal of cancer research and clinical oncology · 2025Pooled it
- Comparison of treatments for preventing lower urinary tract symptoms after BCG immunotherapy of bladder tumors : a systematic review and network meta-analysis.BMC urology · 2025Pooled it
- Clinical, humanistic and economic burden associated with recurrence among patients with early-stage cancers: a systematic literature review.Frontiers in oncology · 2025Pooled it
- Muscle-invasive bladder cancer organ-preserving therapy: systematic review and meta-analysis.World journal of urology · 2018Pooled it
- Effects of Acupoint Application on Lower Urinary Tract Symptoms in Patients Undergoing Intravesical Instillation After Bladder Cancer Surgery: A Randomized Crossover Exploratory Study.Pain research & management · 2026Trial
- Patient satisfaction and feasibility with a novel drug-injectable urethral catheter set for hyaluronic acid administration: a multicenter randomized trial.Scientific reports · 2025Trial
- Efficacy of three BCG strains (Connaught, TICE and RIVM) with or without secondary resection (re-TUR) for intermediate/high-risk non-muscle-invasive bladder cancers: results from a retrospective single-institution cohort analysis.Journal of cancer research and clinical oncology · 2021Trial
- First-in-human outpatient management of recurrent NMIBC with the Multi4 instrument.BJU international · 2026Article
- Clinical indicators combined with spectral CT in differentiating non-muscle-invasive bladder urothelial carcinoma from cystitis glandularis.Abdominal radiology (New York) · 2026Article
- Immunohistochemical assessment of vimentin expression and Ki-67 proliferation index in conventional urothelial carcinoma: a study of 60 Egyptian patients.International urology and nephrology · 2026Article
- Obturator Nerve Block Is Associated with Improved Histopathological Specimen Quality and Fewer Perioperative Complications During TURBT for Lateral Bladder Wall Tumors.Journal of clinical medicine · 2026Article
- Clinicopathological characteristics and prognostic outcomes of bladder urothelial neoplasms in patients under 40 years of age: a multicenter retrospective study.Virchows Archiv : an international journal of pathology · 2026Article
- Impact of spinal versus general anesthesia on dwell time of early immediate intravesical epirubicin administration following transurethral resection of bladder tumor: an observational study.World journal of urology · 2026Observational
- Association ofInternational journal of molecular sciences · 2026Article
- Bladder preservation approach versus radical cystectomy for high-grade non-muscle-invasive bladder cancer: a meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Papillary urothelial tumor of low malignant potential in a pediatric patient: case associated with Poland syndrome.Urology case reports · 2026Article
- Complement tumor-crosstalk: the role of C5a receptors in urothelial carcinomas.Frontiers in immunology · 2026Review
- YouTube as a Resource for Surgical Education: A Content Analysis of Transurethral Bladder Tumor Resection (TURBT) Videos.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Male reproductive and sexual health outcomes following intravesical therapy for non-muscle invasive bladder cancer.World journal of urology · 2025Review
- Diagnostic value of serum DR-70 levels, a new fibrin-related biomarker, in bladder cancer patients.BMC urology · 2025Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 15 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urothelial bladder cancer (UBC) is rare in young patients and as a result little information as to tumor type and clinical course are available. We present clinicopathological data of a large series of patients less than 40 years with bladder carcinoma. We included in this retrospective study covering the period from 1992 to 2013 patients less than 40 years with a first diagnosis of bladder cancer. Lesions were classified according to the WHO 2004 classification by uropathologists of ten centers. Stage, grade, multifocality, smoking habits, recurrence, and survival were studied. The cohort comprised of 152 patients, 113 males and 39 females with a mean age of 33.2 years. The large majority of the patients (142) was diagnosed with an urothelial carcinoma, the ten others with various histopathological diagnoses. In the age group less than 30 years old, 40.3 % of the cases concerned a papillary urothelial neoplasia of low malignant potential (PUNLMP). In the age group over 30 years, the proportion of PUNLMP decreased to 27.2 %. Only 5.6 % of the UBC was associated with carcinoma in situ. In 14.1 %, a high grade muscle invasive UC was found; 7.0 % had lymph node and 4.9 % distant metastasis at time of presentation. Four patients presented with a history of schistosomiasis; all had an infiltrating carcinoma. After initial resection, 36 patients relapsed, 17 % as PUNLMP, 53 % as pTa low grade, and 30 % as pTa-pT2 high grade UC. During follow-up, 6 % of the patients died. PUNLMP is the most frequent entity in this patient group. It is important that the PUNLMP entity is maintained in future classification systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.