Evidence map›Paper›PMID 25697304›Full record

ArticleEpidemiology and infection2015

Using molecular tools to identify the geographical origin of a case of human brucellosis.

J K Muchowski, M S Koylass, A C Dainty, J A Stack, L Perrett, A M Whatmore, C Perrier, S Chircop, N Demicoli, A B Gatt and 2 more

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 3 countries.

J K MuchowskiBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
M S KoylassBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
A C DaintyBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
J A StackBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
L PerrettBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
A M WhatmoreBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
C PerrierBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
S ChircopVeterinary Regulation Directorate,Marsa,Malta.
N DemicoliVeterinary Regulation Directorate,Marsa,Malta.
A B GattHealth Promotion and Disease Prevention Directorate,Msida,Malta.
P A CaruanaMater Dei Hospital,Msida,Malta.
K K GopaulBacterial Characterisation Workgroup,Department of Bacteriology,APHA Weybridge,Addlestone,Surrey,UK.
Veterinary Medicines Directorate · GBMater Dei Hospital · MT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although Malta is historically linked with the zoonosis brucellosis, there had not been a case of the disease in either the human or livestock population for several years. However, in July 2013 a case of human brucellosis was identified on the island. To determine whether this recent case originated in Malta, four isolates from this case were subjected to molecular analysis. Molecular profiles generated using multilocus sequence analysis and multilocus variable number tandem repeat for the recent human case isolates and 11 Brucella melitensis strains of known Maltese origin were compared with others held on in-house and global databases. While the 11 isolates of Maltese origin formed a distinct cluster, the recent human isolation was not associated with these strains but instead clustered with isolates originating from the Horn of Africa. These data was congruent with epidemiological trace-back showed that the individual had travelled to Malta from Eritrea. This work highlights the potential of using molecular typing data to aid in epidemiological trace-back of Brucella isolations and assist in monitoring of the effectiveness of brucellosis control schemes.

Indexed as

Minisatellite RepeatsMultilocus Sequence TypingTravelAfricaBrucella melitensisBrucellosisHumansMaltaMolecular EpidemiologyBrucellabrucellosismolecular epidemiology

Identifiers

PMID25697304
PMCPMC9151018
OpenAlexW2149824425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.