ArticleGut microbes2015
Characterization of the human gut microbiome during travelers' diarrhea.
Article in Gut microbes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.
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Who cites it
89 citing papers in PubMed, 1 synthesis or guideline pooled it, 150 citations in OpenAlex.
- Rome Foundation Working Team Report on Post-Infection Irritable Bowel Syndrome.Gastroenterology · 2019Guideline
- The Effect of a Probiotic on Gut Microbiota Stability and Systemic Well-Being during Short-Term Travel.Journal of microbiology and biotechnology · 2026Trial
- Optimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff.Sports medicine (Auckland, N.Z.) · 2026Review
- Daily sampling reveals rapid microbiota alterations and antimicrobial resistance gene acquisition during intercontinental travel.NPJ biofilms and microbiomes · 2026Article
- Travel microbiota: a novel frontier in travel medicine exploring microbial shifts across transportation modes.Tropical diseases, travel medicine and vaccines · 2026Review
- Broad-spectrum antibiotic treatment reshapes the gut microbiome, resistome, and colonization potential of opportunistic pathogens: a metagenomics study.Gut pathogens · 2026Article
- EnteroaggregativeEcoSal Plus · 2025Review
- Rifaximin as a Therapeutic Ally in the Modulation of Dysbiosis: A Narrative Review of Its Applicability in Gastrointestinal Disorders.GE Portuguese journal of gastroenterology · 2025Review
- Salinity Effects on Aquatic and Host Intestinal Microbiota Dynamics inAnimals : an open access journal from MDPI · 2025Article
- An Asset for Food Safety: The Knowledge Behind the Physiological Alterations Induced by ETEC Enterotoxins.Foods (Basel, Switzerland) · 2025Review
- Fecal gut microbiome alterations and its association with lactose intolerance in children with rotavirus infection-related diarrhea.European journal of pediatrics · 2025Article
- Assessing Zoonotic Risks ofPathogens (Basel, Switzerland) · 2025Article
- A New Dirichlet-Multinomial Mixture Regression Model for the Analysis of Microbiome Data.Statistics in medicine · 2025Article
- Fecal microbiome profiling of children withMicrobiology spectrum · 2025Article
- Agent-based model of the human colon to investigate mechanisms of pathogen colonization resistance.Biophysical journal · 2025Article
- Bacillus coagulans 198 and L-glutamine in combination attenuated intestinal mucositis in a 5-FU-induced BALB/c mouse model via modulation of gut microbial community structure and diversity.Journal of food and drug analysis · 2025Article
- Role of gut microbiome in pathogenesis and treatment of diseases: Multidisciplinary experts' opinion of the Asian Medical Experts Academy (AMEA).Gut microbes reports · 2025Review
- Categorizing and characterizing intestinal dysbiosis: evaluating stool microbial test clinical utility.Frontiers in microbiomes · 2025Article
- High prevalence of enterotoxigenicFrontiers in microbiology · 2025Article
- Saccharomyces yeast postbiotics mitigate mucosal damages from F18Animal microbiome · 2024Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
Alterations in the gut microbiota are correlated with ailments such as obesity, inflammatory bowel disease, and diarrhea. Up to 60% of individuals traveling from industrialized to developing countries acquire a form of secretory diarrhea known as travelers' diarrhea (TD), and enterotoxigenic Escherichia coli (ETEC) and norovirus (NoV) are the leading causative pathogens. Presumably, TD alters the gut microbiome, however the effect of TD on gut communities has not been studied. We report the first analysis of bacterial gut populations associated with TD. We examined and compared the gut microbiomes of individuals who developed TD associated with ETEC, NoV, or mixed pathogens, and TD with no pathogen identified, to healthy travelers. We observed a signature dysbiotic gut microbiome profile of high Firmicutes:Bacteroidetes ratios in the travelers who developed diarrhea, regardless of etiologic agent or presence of a pathogen. There was no significant difference in α-diversity among travelers. The bacterial composition of the microbiota of the healthy travelers was similar to the diarrheal groups, however the β-diversity of the healthy travelers was significantly different than any pathogen-associated TD group. Further comparison of the healthy traveler microbiota to those from healthy subjects who were part of the Human Microbiome Project also revealed a significantly higher Firmicutes:Bacteriodetes ratio in the healthy travelers and significantly different β-diversity. Thus, the composition of the gut microbiome in healthy, diarrhea-free travelers has characteristics of a dysbiotic gut, suggesting that these alterations could be associated with factors such as travel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.