Evidence map›Paper›PMID 25695062›Full record

ArticleBioMed research international2015

Strategy for the management of diabetic macular edema: the European vitreo-retinal society macular edema study.

Ron Adelman, Aaron Parnes, Zofia Michalewska, Barbara Parolini, Claude Boscher, Didier Ducournau

Erratum issuedOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Vitrectomy for center-involved diabetic macular edema.Clinical ophthalmology (Auckland, N.Z.) · 2016
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ron AdelmanYale University School of Medicine, New Haven, CT, USA.
Aaron ParnesEyecare Medical Group, Portland, ME, USA.
Zofia MichalewskaOphthalmic Clinic "Jasne Blonia", Lodz, Poland.ORCID 0000-0001-8376-9218
Barbara ParoliniDepartment of Ophthalmology, S. Anna Hospital, Brescia, Italy.ORCID 0000-0002-7838-6834
Claude BoscherAmerican Hospital of Paris, Paris, France.
Didier DucournauEVRS, Nantes, France.
Eye Care Associates · USHôpital américain de paris · FRYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the efficacy of different therapies in the treatment of diabetic macular edema (DME).

designNonrandomized, multicenter clinical study.

participants86 retina specialists from 29 countries provided clinical information on 2,603 patients with macular edema including 870 patients with DME.

methodsReported data included the type and number of treatment(s) performed, the pre- and posttreatment visual acuities, and other clinical findings. The results were analyzed by the French INSEE (National Institute of Statistics and Economic Studies).

main outcome measuresMean change of visual acuity and mean number of treatments performed.

resultsThe change in visual acuity over time in response to each treatment was plotted in second order polynomial regression trend lines. Intravitreal triamcinolone monotherapy resulted in some improvement in vision. Treatment with threshold or subthreshold grid laser also resulted in minimal vision gain. Anti-VEGF therapy resulted in more significant visual improvement. Treatment with pars plana vitrectomy and internal limiting membrane (ILM) peeling alone resulted in an improvement in vision greater than that observed with anti-VEGF injection alone. In our DME study, treatment with vitrectomy and ILM peeling alone resulted in the better visual improvement compared to other therapies.

Indexed as

Basement MembraneDiabetic RetinopathyDisease ManagementHumansMacular EdemaRetinaVisual AcuityVitrectomy

Identifiers

PMID25695062
PMCPMC4324105
OpenAlexW2026209404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.