Evidence map›Paper›PMID 25694966›Full record

ArticleQuantitative imaging in medicine and surgery2015

Anterior segment optical coherence tomography evaluation of ocular graft-versus-host disease: a case study.

Peng Li, Yichen Sun, Sepideh Hariri, Zhehai Zhou, Yoshihiro Inamoto, Stephanie J Lee, Tueng T Shen, Ruikang K Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Peng Li1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Yichen Sun1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Sepideh Hariri1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Zhehai Zhou1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Yoshihiro Inamoto1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Stephanie J Lee1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Tueng T Shen1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Ruikang K Wang1 Department of Bioengineering, 2 Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA ; 3 Buddhist Tzu Chi General Hospital, Taipei Division, New Taipei, Taiwan ; 4 Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Fred Hutch Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore ocular graft-versus-host disease (GVHD), anterior segment optical coherence tomography (AS-OCT) imaging of eyelids, tear meniscus, cornea and conjunctiva is performed in subsequent sessions on a patient who has ocular GVHD after allogeneic related donor stem cell transplant. The OCT results are presented together with those from a normal subject. OCT imaging is promising in visualizing several ocular GVHD manifestations, such as abnormal meibomian gland orifice (MGO), conjunctival keratinization, conjunctival hyperemia and chemosis, corneal epithelium opacification, thinning and sloughing. This case study demonstrates the capability of AS-OCT in the imaging and monitoring of ocular GVHD, which may be useful in the development of current ocular GVHD staging system and the clinical management for GVHD treatment.

Indexed as

Medical and biological imagingocular graft-versus-host disease (GVHD)ophthalmologyoptical coherence tomography (OCT)

Identifiers

PMID25694966
PMCPMC4312287
OpenAlexW344461748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.