Evidence map›Paper›PMID 25694953›Full record

ArticleQuantitative imaging in medicine and surgery2015

The application of backscattered ultrasound and photoacoustic signals for assessment of bone collagen and mineral contents.

Bahman Lashkari, Lifeng Yang, Andreas Mandelis

Open access · greenAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Development of a semi-anthropomorphic photoacoustic calcaneus phantom based on nano computed tomography and stereolithography 3D printing.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
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  5. Piezoelectric and Opto-Acoustic Material Properties of Bone.Advances in experimental medicine and biology · 2022
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  13. FGF-2 Gene Polymorphism in Osteoporosis among Guangxi's Zhuang Chinese.International journal of molecular sciences · 2017
    Article
  14. Article
  15. Comparison between the gold standard DXA with calcaneal quantitative ultrasound based-strategy (QUS) to detect osteoporosis in an HIV infected cohort.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bahman Lashkari1 Center for Advanced Diffusion-Wave Technologies (CADIFT), Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada ; 2 School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu 610054, China.
Lifeng Yang1 Center for Advanced Diffusion-Wave Technologies (CADIFT), Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada ; 2 School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu 610054, China.
Andreas Mandelis1 Center for Advanced Diffusion-Wave Technologies (CADIFT), Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada ; 2 School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu 610054, China.
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study examines the backscattered ultrasound (US) and back-propagating photoacoustic (PA) signals from trabecular bones, and their variations with reduction in bone minerals and collagen content. While the collagen status is directly related to the strength of the bone, diagnosis of its condition using US remains a challenge.

methodsFor both PA and US methods, coded-excitation signals and matched filtering were utilized to provide high sensitivity of the detected signal. The optical source was a 805-nm CW laser and signals were detected employing a 2.2-MHz ultrasonic transducer. Bone decalcification and decollagenization were induced with mild ethylenediaminetetraacetic acid (EDTA) and sodium hypochlorite solutions, respectively.

resultsThe PA and US signals were measured on cattle bones, and apparent integrated backscatter/back-propagating (AIB) parameters were compared before and after demineralization and decollagenization.

conclusionsThe results show that both PA and US are sensitive to mineral changes. In addition, PA is also sensitive to changes in the collagen content of the bone, but US is not significantly sensitive to these changes.

Indexed as

bone mineral density (BMD)cancellous bonecollagen contentOsteoporosisphotoacoustic (PA)quantitative ultrasound (QUS)ultrasonic backscattering

Identifiers

PMID25694953
PMCPMC4312292
OpenAlexW2203847113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.