Evidence map›Paper›PMID 25694668›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2015

Plasma serotonin in horses undergoing surgery for small intestinal colic.

Sara C Torfs, An A Maes, Catherine J Delesalle, Bart Pardon, Siska M Croubels, Piet Deprez

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sara C TorfsDepartment of Large Animal Internal Medicine and Clinical Biology (Torfs, Delesalle, Pardon, Deprez), Department of Pharmacology, Toxicology and Biochemistry (Maes, Croubels), Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820, Merelbeke, Belgium; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, NL-3584 CL, Utrecht, The Netherlands (Delesalle).
An A MaesDepartment of Large Animal Internal Medicine and Clinical Biology (Torfs, Delesalle, Pardon, Deprez), Department of Pharmacology, Toxicology and Biochemistry (Maes, Croubels), Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820, Merelbeke, Belgium; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, NL-3584 CL, Utrecht, The Netherlands (Delesalle).
Catherine J DelesalleDepartment of Large Animal Internal Medicine and Clinical Biology (Torfs, Delesalle, Pardon, Deprez), Department of Pharmacology, Toxicology and Biochemistry (Maes, Croubels), Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820, Merelbeke, Belgium; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, NL-3584 CL, Utrecht, The Netherlands (Delesalle).
Bart PardonDepartment of Large Animal Internal Medicine and Clinical Biology (Torfs, Delesalle, Pardon, Deprez), Department of Pharmacology, Toxicology and Biochemistry (Maes, Croubels), Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820, Merelbeke, Belgium; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, NL-3584 CL, Utrecht, The Netherlands (Delesalle).
Siska M CroubelsDepartment of Large Animal Internal Medicine and Clinical Biology (Torfs, Delesalle, Pardon, Deprez), Department of Pharmacology, Toxicology and Biochemistry (Maes, Croubels), Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820, Merelbeke, Belgium; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, NL-3584 CL, Utrecht, The Netherlands (Delesalle).
Piet DeprezDepartment of Large Animal Internal Medicine and Clinical Biology (Torfs, Delesalle, Pardon, Deprez), Department of Pharmacology, Toxicology and Biochemistry (Maes, Croubels), Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820, Merelbeke, Belgium; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, NL-3584 CL, Utrecht, The Netherlands (Delesalle).
Ghent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared serotonin concentrations in platelet poor plasma (PPP) from healthy horses and horses with surgical small intestinal (SI) colic, and evaluated their association with postoperative ileus, strangulation and non-survival. Plasma samples (with EDTA) from 33 horses with surgical SI colic were collected at several pre- and post-operative time points. Serotonin concentrations were determined using liquid-chromatography tandem mass spectrometry. Results were compared with those for 24 healthy control animals. The serotonin concentrations in PPP were significantly lower (P < 0.01) in pre- and post-operative samples from surgical SI colic horses compared to controls. However, no association with postoperative ileus or non-survival could be demonstrated at any time point. In this clinical study, plasma serotonin was not a suitable prognostic factor in horses with SI surgical colic.

Indexed as

AnimalsColicFemaleHorse DiseasesHorsesIntestine, SmallMalePlatelet ActivationSerotoninSerotonin

Identifiers

PMID25694668
PMCPMC4298271
OpenAlexW178110153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.