ArticleProceedings. Biological sciences2015
Side-by-side secretion of Late Palaeozoic diverged courtship pheromones in an aquatic salamander.
Article in Proceedings. Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 26 citations in OpenAlex.
- Histological and Gene Expression Analyses of the Arm and Finger Macroglands of Two Hyloxalus Frogs (Dendrobatidae).Molecular ecology · 2025Article
- Genetic Diversity of Sodefrin-Variant Pheromones and Pheromone Responsiveness in Subspecies of the Japanese Sword-Tail NewtAnimals : an open access journal from MDPI · 2025Article
- Recurrent Co-Option and Recombination of Cytokine and Three Finger Proteins in Multiple Reproductive Tissues Throughout Salamander Evolution.Frontiers in cell and developmental biology · 2022Article
- Love bites: male frogs (Plectrohyla, Hylidae) use teeth scratching to deliver sodefrin precursor-like factors to females during amplexus.Frontiers in zoology · 2021Article
- Pheromone Gene Diversification and the Evolution of Courtship Glands in Plethodontid Salamanders.Journal of molecular evolution · 2021Article
- Pheromonal communication in urodelan amphibians.Cell and tissue research · 2021Review
- On the identification of paedomorphic and overwintering larval newts based on cloacal shape: review and guidelines.Current zoology · 2017Article
- Beyond sodefrin: evidence for a multi-component pheromone system in the model newt Cynops pyrrhogaster (Salamandridae).Scientific reports · 2016Article
- From molecules to mating: Rapid evolution and biochemical studies of reproductive proteins.Journal of proteomics · 2016Review
- Courtship Pheromone Use in a Model Urodele, the Mexican Axolotl (Ambystoma mexicanum).Scientific reports · 2016Article
- Article
- High pheromone diversity in the male cheek gland of the red-spotted newt Notophthalmus viridescens (Salamandridae).BMC evolutionary biology · 2015Article
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Males of the advanced salamanders (Salamandroidea) attain internal fertilization without a copulatory organ by depositing a spermatophore on the substrate in the environment, which females subsequently take up with their cloaca. The aquatically reproducing modern Eurasian newts (Salamandridae) have taken this to extremes, because most species do not display close physical contact during courtship, but instead largely rely on females following the male track at spermatophore deposition. Although pheromones have been widely assumed to represent an important aspect of male courtship, molecules able to induce the female following behaviour that is the prelude for successful insemination have not yet been identified. Here, we show that uncleaved sodefrin precursor-like factor (SPF) protein pheromones are sufficient to elicit such behaviour in female palmate newts (Lissotriton helveticus). Combined transcriptomic and proteomic evidence shows that males simultaneously tail-fan multiple ca 20 kDa glycosylated SPF proteins during courtship. Notably, molecular dating estimates show that the diversification of these proteins already started in the late Palaeozoic, about 300 million years ago. Our study thus not only extends the use of uncleaved SPF proteins outside terrestrially reproducing plethodontid salamanders, but also reveals one of the oldest vertebrate pheromone systems.
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