Evidence map›Paper›PMID 25694591›Full record

ArticleJournal of virology2015

Expression of the novel hepatitis C virus core+1/ARF protein in the context of JFH1-based replicons.

Ioly Kotta-Loizou, Ioannis Karakasiliotis, Niki Vassilaki, Panagiotis Sakellariou, Ralf Bartenschlager, Penelope Mavromara

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Hepatitis C Virus Translation Regulation.International journal of molecular sciences · 2020
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ioly Kotta-LoizouMolecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece.
Ioannis KarakasiliotisMolecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece.
Niki VassilakiMolecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece.
Panagiotis SakellariouMolecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece.
Ralf BartenschlagerDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.
Penelope MavromaraMolecular Virology Laboratory, Hellenic Pasteur Institute, Athens, Greece Department of Molecular Biology and Genetics, Democritus University of Thrace, Thrace, Greece penelopm@pasteur.gr.
Pasteur Hellenic Institute · GRDemocritus University of Thrace · GRHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus contains a second open reading frame within the core gene, designated core+1/ARF. Here we demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (short), with different kinetics.

Indexed as

Gene ExpressionCell LineGene Expression ProfilingHepacivirusHepatocytesHumansProtein IsoformsRepliconViral Core Proteinshepatitis C protein F, Hepatitis C virusProtein IsoformsViral Core Proteins

Identifiers

PMID25694591
PMCPMC4403472
OpenAlexW2079643828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.