Trial reportBMJ open2015
A tool for prediction of risk of rehospitalisation and mortality in the hospitalised elderly: secondary analysis of clinical trial data.
Trial report in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Medication review in hospitalised patients to reduce morbidity and mortality.The Cochrane database of systematic reviews · 2023Pooled it
- Detection tools for prediction and identification of adverse drug reactions in older patients: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Pooled it
- Utility of models to predict 28-day or 30-day unplanned hospital readmissions: an updated systematic review.BMJ open · 2016Pooled it
- Prediction tools to prioritise hospitalised adult patients at risk of drug related problems: An umbrella review.PLOS digital health · 2026Article
- The doMESTIC RISK Tool: Prioritising Home-Care Patients for Clinical Pharmacy Services with the Help of a Delphi Study.Nursing reports (Pavia, Italy) · 2025Article
- Potentially inappropriate prescribing in elderly patients with epilepsy at two referral hospitals in Ethiopia.Frontiers in medicine · 2024Article
- Effectiveness of pharmacist-led medication reconciliation on medication errors at hospital discharge and healthcare utilization in the next 30 days: a pragmatic clinical trial.Frontiers in pharmacology · 2024Article
- Discharge Planning of Older Persons from Hospital: Comparison of Observed Practice to Recommended Best Practice.Healthcare (Basel, Switzerland) · 2022Article
- External validation of the PAR-Risk Score to assess potentially avoidable hospital readmission risk in internal medicine patients.PloS one · 2021Article
- Medication-related hospital admissions and readmissions in older patients: an overview of literature.International journal of clinical pharmacy · 2020Review
- Screening Tools Used by Clinical Pharmacists to Identify Elderly Patients at Risk of Drug-Related Problems on Hospital Admission: A Systematic Review.Pharmacy (Basel, Switzerland) · 2020Review
- Observational
- Development of a predictive score for potentially avoidable hospital readmissions for general internal medicine patients.PloS one · 2019Observational
- The Effect of Computerized Physician Order Entry Template Modifications on the Administration of High-Risk Medications in Older Adults in the Emergency Department.Drugs & aging · 2017Article
- Older adults and high-risk medication administration in the emergency department.Drug, healthcare and patient safety · 2017Article
- Early rehospitalizations of frail elderly patients - the role of medications: a clinical, prospective, observational trial.Drug, healthcare and patient safety · 2017Article
- Potentially inappropriate prescribing according to STOPP and START and adverse outcomes in community-dwelling older people: a prospective cohort study.British journal of clinical pharmacology · 2016Article
- The Use of Opioid Analgesics following Common Upper Extremity Surgical Procedures: A National, Population-Based Study.Plastic and reconstructive surgery · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo construct and internally validate a risk score, the '80+ score', for revisits to hospital and mortality for older patients, incorporating aspects of pharmacotherapy. Our secondary aim was to compare the discriminatory ability of the score with that of three validated tools for measuring inappropriate prescribing: Screening Tool of Older Person's Prescriptions (STOPP), Screening Tool to Alert doctors to Right Treatment (START) and Medication Appropriateness Index (MAI).
settingTwo acute internal medicine wards at Uppsala University hospital. Patient data were used from a randomised controlled trial investigating the effects of a comprehensive clinical pharmacist intervention.
participantsData from 368 patients, aged 80 years and older, admitted to one of the study wards. PRIMARY OUTCOME MEASURE: Time to rehospitalisation or death during the year after discharge from hospital. Candidate variables were selected among a large number of clinical and drug-specific variables. After a selection process, a score for risk estimation was constructed. The 80+ score was internally validated, and the discriminatory ability of the score and of STOPP, START and MAI was assessed using C-statistics.
resultsSeven variables were selected. Impaired renal function, pulmonary disease, malignant disease, living in a nursing home, being prescribed an opioid or being prescribed a drug for peptic ulcer or gastroesophageal reflux disease were associated with an increased risk, while being prescribed an antidepressant drug (tricyclic antidepressants not included) was linked to a lower risk of the outcome. These variables made up the components of the 80+ score. The C-statistics were 0.71 (80+), 0.57 (STOPP), 0.54 (START) and 0.63 (MAI).
conclusionsWe developed and internally validated a score for prediction of risk of rehospitalisation and mortality in hospitalised older people. The score discriminated risk better than available tools for inappropriate prescribing. Pending external validation, this score can aid in clinical identification of high-risk patients and targeting of interventions.
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