ArticleHypertension research : official journal of the Japanese Society of Hypertension2015
Glucose and the risk of hypertension in first-degree relatives of patients with type 2 diabetes.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The Burden of Multiple Metabolic Diseases and Their Impact on Cardiovascular and Kidney Complications in Type 2 Diabetes: A 10-Year Real-World Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Association of methylation risk score with incident type 2 diabetes mellitus: A nested case-control study.Journal of diabetes · 2024Article
- A higher TyG index level is more likely to have enhanced incidence of T2DM and HTN comorbidity in elderly Chinese people: a prospective observational study from the reaction study.Diabetology & metabolic syndrome · 2024Article
- Association of glycemic control with hypertension in patients with diabetes: a population-based longitudinal study.BMC cardiovascular disorders · 2023Article
- Associations between triglyceride-glucose index and different hypertension subtypes: A population-based study in China.Frontiers in cardiovascular medicine · 2022Article
- Risk of hypertension in middle-aged and elderly participants with newly diagnosed type 2 diabetes and prediabetes.BMJ open diabetes research & care · 2020Article
- A high triglyceride glucose index is more closely associated with hypertension than lipid or glycemic parameters in elderly individuals: a cross-sectional survey from the Reaction Study.Cardiovascular diabetology · 2020Article
- Association of Insulin Resistance, Plasma Glucose Level, and Serum Insulin Level With Hypertension in a Population With Different Stages of Impaired Glucose Metabolism.Journal of the American Heart Association · 2020Article
- Prevalence and predictors of prediabetes and its coexistence with high blood pressure in first-degree relatives of patients with type 2 diabetes: A 9-year cohort study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020Article
- The relationship between obesity and hypertension: an updated comprehensive overview on vicious twins.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
- Hypertension with diabetes mellitus: significance from an epidemiological perspective for Japanese.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
- Association between changes in systolic blood pressure and incident diabetes in a community-based cohort study in Korea.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
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3 authors.
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Abstract
To test the hypothesis that plasma glucose (PG) levels is associated with the incidence of hypertension (HT) in nondiabetic and non-hypertensive first-degree relatives (FDR) of people with type 2 diabetes (T2D). A total of 1089 FDR without diabetes and/or HT of consecutive patients with T2D 30-70 years old were examined and followed for a mean (s.d.) of 6.9 (1.7) years for HT incidence. At baseline and through follow-up, participants underwent a standard 75 gm 2-h oral glucose tolerance test. HT was defined according to the criteria of the Seventh Report of Joint National Committee. We used Cox proportional hazard models to estimate hazard ratio for incident HT and plotted a receiver operating characteristic curve to assess discrimination. The PG levels at baseline were associated with incidence of HT, independently of age, gender, obesity and high cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, education and systolic blood pressure. Those with impaired glucose tolerance were 54% (hazard ratio 1.54; 95% confidence interval (CI) 1.33, 1.77) more likely to develop HT than those with normal glucose tolerance. Those with impaired fasting glucose were also 23% (hazard ratio 1.23; 95% CI 1.01, 1.50) more likely to develop HT. High PG levels were consistently associated with incident HT.
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