ReviewHypertension research : official journal of the Japanese Society of Hypertension2015
Environmental origins of hypertension: phylogeny, ontogeny and epigenetics.
Review in Hypertension research : official journal of the Japanese Society of Hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Contrastive Machine Learning to Quantify Hypertensive Multiorgan Damage and Identify New Disease Phenotypes: A Multinational Multimodal Study.Circulation · 2026Article
- White blood cell and platelet distribution widths are associated with hypertension: data mining approaches.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Microbial influence on blood pressure: unraveling the complex relationship for health insights.Microbiome research reports · 2024Article
- A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS).Archives of toxicology · 2023Review
- Novel Insights on Dietary Polyphenols for Prevention in Early-Life Origins of Hypertension: A Review Focusing on Preclinical Animal Models.International journal of molecular sciences · 2022Review
- Developmental and Early Life Origins of Hypertension: Preventive Aspects of Melatonin.Antioxidants (Basel, Switzerland) · 2022Review
- Article
- The Amphibious Mudskipper: A Unique Model Bridging the Gap of Central Actions of Osmoregulatory Hormones Between Terrestrial and Aquatic Vertebrates.Frontiers in physiology · 2018Review
- Association between mean platelet volume and hypertension incidence.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Mesenchymal-to-epithelial transition in the placental tissues of patients with preeclampsia.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Precision medicine in cardiology.Nature reviews. Cardiology · 2016Review
- Prenatal hypoxia in rats increased blood pressure and sympathetic drive of the adult offspring.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension and renal parenchymal disease are intricately linked. Primary renal parenchymal disease can impact on sodium and volume regulation and lead to hypertension, while arterial hypertension can induce renal parenchymal injury and precipitate renal dysfunction. The examination for clues to the environmental origins of renal disease and hypertension necessitates an approach that integrates epidemiology, clinical medicine, developmental biology, environmental science and epigenetics, such that the manner in which genes and the environment interact can be better understood to pave the way for innovative management paradigms with regards to prevention, diagnosis and treatment. This review summarizes the extant literature and provides cogent arguments for the need to evaluate chronic adult onset disease models such as hypertension and renal disease from the modern perspective that takes into account prenatal exposures, the intrauterine environment and development, postnatal growth and transgenerational epigenetic modifications with their attendant future disease risk from the individual to the population level.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.