ArticleMolecular & cellular proteomics : MCP2015
DYn-2 Based Identification of Arabidopsis Sulfenomes.
Article in Molecular & cellular proteomics : MCP, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 84 citations in OpenAlex.
- Emerging concepts of reactive oxygen species functions in plants.Biochemical Society transactions · 2026Review
- Oxidative stress-induced CDO1 glutathionylation regulates cysteine metabolism and sustains redox homeostasis under ionizing radiation.Redox biology · 2025Article
- Redox regulation of glutamate-1-semialdehyde aminotransferase modulates the synthesis of 5-aminolevulinic acid in Arabidopsis.Frontiers in plant science · 2025Article
- Hydrogen peroxide participates in leaf senescence by inhibiting CHLI1 activity.Plant cell reports · 2024Article
- Hydrogen peroxide sulfenylates and inhibits the photorespiratory enzyme PGLP1 to modulate plant thermotolerance.Plant communications · 2024Article
- Photorespiration: regulation and new insights on the potential role of persulfidation.Journal of experimental botany · 2023Review
- Comparative oxidation proteomics analyses suggest redox regulation of cytosolic translation in rice leaves upon Magnaporthe oryzae infection.Plant communications · 2023Article
- Salt stress-induced chloroplastic hydrogen peroxide stimulates pdTPI sulfenylation and methylglyoxal accumulation.The Plant cell · 2023Article
- HPlant, cell & environment · 2023Review
- More indications for redox-sensitive cysteine residues of the Arabidopsis 5-aminolevulinate dehydratase.Frontiers in plant science · 2023Article
- Identification of Peroxisome-Derived Hydrogen Peroxide-Sensitive Target Proteins Using a YAP1C-Based Genetic Probe.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Thiol-based Oxidative Posttranslational Modifications (OxiPTMs) of Plant Proteins.Plant & cell physiology · 2022Review
- How to Cope with the Challenges of Environmental Stresses in the Era of Global Climate Change: An Update on ROS Stave off in Plants.International journal of molecular sciences · 2022Review
- Topology of the redox network during induction of photosynthesis as revealed by time-resolved proteomics in tobacco.Science advances · 2021Article
- Measuring ROS and redox markers in plant cells.RSC chemical biology · 2021Review
- Plasticity in plastid redox networks: evolution of glutathione-dependent redox cascades and glutathionylation sites.BMC plant biology · 2021Article
- Contemporary proteomic strategies for cysteine redoxome profiling.Plant physiology · 2021Review
- Mitochondrial redox systems as central hubs in plant metabolism and signaling.Plant physiology · 2021Review
- Mapping the plant proteome: tools for surveying coordinating pathways.Emerging topics in life sciences · 2021Review
- Cysteine modifications (oxPTM) and protein sulphenylation-mediated sulfenome expression in plants: evolutionary conserved signaling networks?Plant signaling & behavior · 2021Article
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Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
Abstract
Identifying the sulfenylation state of stressed cells is emerging as a strategic approach for the detection of key reactive oxygen species signaling proteins. Here, we optimized an in vivo trapping method for cysteine sulfenic acids in hydrogen peroxide (H2O2) stressed plant cells using a dimedone based DYn-2 probe. We demonstrated that DYn-2 specifically detects sulfenylation events in an H2O2 dose- and time-dependent way. With mass spectrometry, we identified 226 sulfenylated proteins after H2O2 treatment of Arabidopsis cells, residing in the cytoplasm (123); plastid (68); mitochondria (14); nucleus (10); endoplasmic reticulum, Golgi and plasma membrane (7) and peroxisomes (4). Of these, 123 sulfenylated proteins have never been reported before to undergo cysteine oxidative post-translational modifications in plants. All in all, with this DYn-2 approach, we have identified new sulfenylated proteins, and gave a first glance on the locations of the sulfenomes of Arabidopsis thaliana.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.