ArticleEuropean radiology2015
Caveat of measuring perfusion indexes using intravoxel incoherent motion magnetic resonance imaging in the human brain.
Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Impact of hypertension on cerebral microvascular structure in CPAP-treated obstructive sleep apnoea patients: a diffusion magnetic resonance imaging study.Neuroradiology · 2019Trial
- Assessment of Cerebral Perfusion Asymmetry in Chronic Migraine Patients Using Intravoxel Incoherent Motion (IVIM)-Derived Pseudodiffusion Coefficient and Perfusion Fraction.NMR in biomedicine · 2026Article
- Brain protein burden is related to intravoxel incoherent motion: PET-MR imaging study.Frontiers in neuroscience · 2026Article
- Review
- A Method for Imaging the Ischemic Penumbra with MRI Using Intravoxel Incoherent Motion.AJNR. American journal of neuroradiology · 2025Article
- Intravoxel incoherent motion imaging and dynamic susceptibility contrast perfusion MRI in differentiation between recurrent intracranial tumor and treatment-induced changes.Neuroradiology · 2025Observational
- Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements.NMR in biomedicine · 2024Review
- Correlation between diffusion-weighted image-derived parameters and dynamic contrast-enhanced magnetic resonance imaging-derived parameters in the orofacial region.Acta radiologica open · 2024Article
- Intravoxel incoherent motion for differentiating residual/recurrent tumor from post-treatment change in patients with high-grade glioma.The neuroradiology journal · 2023Article
- Quantitative perfusion and water transport time model from multiJournal of medical imaging (Bellingham, Wash.) · 2023Article
- Associations between microstructural tissue changes, white matter hyperintensity severity, and cognitive impairment: an intravoxel incoherent motion imaging study.Frontiers in aging neuroscience · 2023Article
- Crossed cerebellar diaschisis after acute ischemic stroke detected by intravoxel incoherent motion magnetic resonance imaging.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Intravoxel Incoherent Motion Magnetic Resonance Imaging Used in Preoperative Screening of High-Risk Patients With Moyamoya Disease Who May Develop Postoperative Cerebral Hyperperfusion Syndrome.Frontiers in neuroscience · 2022Article
- A Fast Protocol for Multiparametric Characterisation of Diffusion in the Brain and Brain Tumours.Frontiers in oncology · 2021Article
- Signal to noise and b-value analysis for optimal intra-voxel incoherent motion imaging in the brain.PloS one · 2021Article
- Optimal Model Mapping for Intravoxel Incoherent Motion MRI.Frontiers in human neuroscience · 2021Article
- Impact of b-Value Sampling Scheme on Brain IVIM Parameter Estimation in Healthy Subjects.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2020Article
- Simplified perfusion fraction from diffusion-weighted imaging in preoperative prediction of IDH1 mutation in WHO grade II-III gliomas: comparison with dynamic contrast-enhanced and intravoxel incoherent motion MRI.Radiology and oncology · 2020Article
- Preliminary Study of Subclinical Brain Alterations in Patients With Asymptomatic Carotid Vulnerable Plaques Using Intravoxel Incoherent Motion Imaging by Voxelwise Comparison: A Study of Whole-Brain Imaging Measures.Frontiers in neuroscience · 2020Article
- Intravoxel incoherent motion perfusion in patients with Moyamoya disease: comparison withActa radiologica open · 2019Article
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5 authors.
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Abstract
objectivesTo numerically and experimentally investigate the robustness of intravoxel incoherent motion (IVIM) magnetic resonance imaging in measuring perfusion indexes in the human brain.
methodsEighteen healthy volunteers were imaged on a 3 T clinical system. Data of IVIM imaging (12 b-values ranging from 0 to 1000 s/mm(2), 12 repetitions) were fitted with a bi-exponential model to extract blood volume fraction (f) and pseudo-diffusion coefficient (D*). The robustness of measurement was assessed by bootstrapping. Dynamic susceptibility contrast (DSC) imaging and arterial spin-labelling (ASL) imaging were performed for cross-modal comparison. Numerical simulations were performed to assess the accuracy and precision of f and D* estimates at varied signal-to-noise ratio (SNRb1000).
resultsBased on our experimental setting (SNRb1000 ~ 30), the average error/variability is ~5 %/25 % for f and ~100 %/30 % for D* in gray matter, and ~10 %/50 % for f and ~300 %/60 % for D* in white matter. Correlation was found between f and DSC-derived cerebral blood volume in gray matter (r = 0.29 - 0.48 across subjects, p < 10(-5)), but not in white matter. No correlation was found between f-D* product and ASL-derived cerebral blood flow.
conclusionsf may provide noninvasive measurement of cerebral blood volume, particularly in gray matter. D* has limited robustness and should be interpreted with caution. KEY POINTS: • A minimum SNR b1000 of 30 is recommended for reliable IVIM imaging. • f may provide noninvasive measurement of cerebral blood volume. • f correlates with CBV DSC in gray matter. • There is no correlation between fD* and CBF ASL . • D* has limited robustness and should be interpreted with caution.
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