Evidence map›Paper›PMID 25693666›Full record

ArticleEuropean radiology2015

Evaluation of whole body Ultralow-Dose CT for the assessment of ventriculoperitoneal shunt complications: an experimental ex-vivo study in a swine model.

Ahmed Othman, Hussam A Hamou, Rastislav Pjontek, Saif Afat, Hans Clusmann, Martin Wiesmann, Marc A Brockmann

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Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ahmed OthmanDepartment of Diagnostic and Interventional Neuroradiology, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany, ahmed.e.othman@googlemail.com.
Hussam A Hamou
Rastislav Pjontek
Saif Afat
Hans Clusmann
Martin Wiesmann
Marc A Brockmann
RWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the suitability of whole body Ultralow-dose CT (ULD-CT) as a diagnostic tool for the evaluation of ventriculoperitoneal shunt (VP-shunt) complications with special regards to radiation dose and image quality.

methodsFourteen VP-shunts were implanted in 7 swine cadavers (weight: 55-70 kg). Twenty-two mechanical complications (extracranial and extraperitoneal malpositioning, breakages, disconnections) were induced in nine VP-shunts. Ten ULD-CT scans with different parameters (tube voltage: 80, 100, 120 kV; tube current: 20 or 50 mAs; Pitch (P): 1 or 1.5) were acquired; the combination of 120 kV and 50 mAs was omitted. Radiation dose estimation, blinded readings, and quantitative and qualitative assessment of the CT-data were performed.

resultsEffective radiation doses varied between 0.44 ± 0.06 and 2.55 ± 0.35 mSv. ULD-CT protocols provided a mean sensitivity (i.e., correctly detected shunt complications) of 98.2 %. Unnoticed or incorrectly identified complications did not exceed one complication (4.5 %) in any ULD-CT protocol. Diagnostic confidence was sufficient for all ULD-CT protocols except for protocols with 80 kV and 20 mAs.

conclusionsULD-CT allows accurate detection of VP-shunt complications at radiation doses similar or lower than reported for a radiographic shunt series. At the tested radiation dose levels, ULD-CT thus provides an alternative to a radiographic shunt series. KEY POINTS: • Ultralow-dose CT accurately detects Ventriculoperitoneal Shunt complications. • Radiation dosage is similar or lower than reported for a radiographic shunt series. • Ultralow-dose CT potentially shortens the diagnostic process when shunt complications are suspected.

Indexed as

AnimalsDisease Models, AnimalRadiation DosageSignal-To-Noise RatioSus scrofaSwineTomography, X-Ray ComputedVentriculoperitoneal ShuntWhole Body Imaging

Identifiers

PMID25693666
OpenAlexW2072466053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.