Evidence map›Paper›PMID 25692698›Full record

ArticleImmunity2015

Immune complexes: not just an innocent bystander in chronic viral infection.

Taia T Wang, Jeffrey V Ravetch

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Article
  9. Article
  10. Article
  11. Vasculitis in Cystic Fibrosis.Frontiers in pediatrics · 2020
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Taia T WangThe Laboratory of Molecular Genetics and Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA.
Jeffrey V RavetchThe Laboratory of Molecular Genetics and Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA. Electronic address: ravetch@mail.rockefeller.edu.
Rockefeller University · US

Funding

Transforming Translational Science and Education to Benefit Human HealthUL1TR000043 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY · 2012 to 2015
$26.8M
Transforming Translational Science and Education to Benefit Human HealthKL2TR000151 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY · 2012 to 2015
$2.1M
NCATS NIH HHS KL2TR000151NCATS NIH HHS UL1 TR000043
6 · The paper itself

Abstract

Understanding of how persistent viral infection impacts humoral immunity is incomplete. In this issue of Immunity, Wieland et al. (2015) and Yamada et al. (2015) find that high amounts of IgG-antigen complexes formed during chronic lymphocytic choriomeningitis infection can interfere with Fcγ-receptor-mediated effector activities, potentially contributing to immune dysfunction.

Indexed as

Lymphocyte DepletionAnimalsAntibodies, ViralAntigen-Antibody ComplexImmune EvasionLymphocytic ChoriomeningitisReceptors, IgGAntibodies, ViralAntigen-Antibody ComplexReceptors, IgG

Identifiers

PMID25692698
OpenAlexW2061114071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.