ArticleChildren (Basel, Switzerland)2015
Impairments that influence physical function among survivors of childhood cancer.
Article in Children (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Effectiveness of home-based exercise programs in children with acute lymphoblastic leukemia: A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Physical activity and fitness among pediatric cancer survivors: a meta-analysis of observational studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- Long-term risk of cardiovascular mortality in lymphoma survivors: A systematic review and meta-analysis.Cancer medicine · 2018Pooled it
- Barriers to Occupational and Physical Therapy Utilization for Children With Cancer.Cancer medicine · 2026Article
- Family environment variables and related health outcomes in children and adolescent and younger adults affected by cancer: a scoping review.Frontiers in psychology · 2026Review
- Extended Reality Gaming for Exercise and Mindfulness Throughout Pediatric Cancer Rehabilitation: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2024Article
- Cardiorespiratory fitness and health-related quality of life in survivors of childhood central nervous system tumours.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Effects of Exercise and Physical Activity Levels on Childhood Cancer: An Umbrella Review.Healthcare (Basel, Switzerland) · 2023Review
- Article
- Skeletal Muscle Measurements in Pediatric Hematology and Oncology: Essential Components to a Comprehensive Assessment.Children (Basel, Switzerland) · 2023Review
- Article
- Feasibility and benefits of a videoconferencing-based home exercise programme for paediatric cancer survivors during the coronavirus disease 2019 pandemic.European journal of cancer care · 2022Article
- Design and Evaluation of an Outdoor Exercise Program for Pediatric Cancer Survivors.Children (Basel, Switzerland) · 2022Article
- A View of the Development of Patient-Reported Outcomes Measures, Their Clinical Integration, Electronification, and Potential Impact on Rehabilitation Service Delivery.Archives of physical medicine and rehabilitation · 2022Article
- Effects of strength exercise interventions on activities of daily living, motor performance, and physical activity in children and adolescents with leukemia or non-Hodgkin lymphoma: Results from the randomized controlled ActiveADL Study.Frontiers in pediatrics · 2022Article
- Article
- Short-Term Consequences of Pediatric Anti-cancer Treatment Regarding Blood Pressure, Motor Performance, Physical Activity and Reintegration Into Sports Structures.Frontiers in pediatrics · 2020Article
- Physical Rehabilitation Practices for Children and Adolescents with Cancer in Canada.Physiotherapy Canada. Physiotherapie Canada · 2020Article
- Article
- Physical training interventions for children and teenagers affected by acute lymphoblastic leukemia and related treatment impairments.Oncotarget · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Children treated for cancer are at increased risk of developing chronic health conditions, some of which may manifest during or soon after treatment while others emerge many years after therapy. These health problems may limit physical performance and functional capacity, interfering with participation in work, social, and recreational activities. In this review, we discuss treatment-induced impairments in the endocrine, musculoskeletal, neurological, and cardiopulmonary systems and their influence on mobility and physical function. We found that cranial radiation at a young age was associated with broad range of chronic conditions including obesity, short stature, low bone mineral density and neuromotor impairments. Anthracyclines and chest radiation are associated with both short and long-term cardiotoxicity. Although numerous chronic conditions are documented among individuals treated for childhood cancer, the impact of these conditions on mobility and function are not well characterized, with most studies limited to survivors of acute lymphoblastic leukemia and brain tumors. Moving forward, further research assessing the impact of chronic conditions on participation in work and social activities is required. Moreover, interventions to prevent or ameliorate the loss of physical function among children treated for cancer are likely to become an important area of survivorship research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.