ReviewInternational journal of hepatology2015
Mystery of hepatitis e virus: recent advances in its diagnosis and management.
Review in International journal of hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 53 citations in OpenAlex.
- Seroprevalence of hepatitis E virus in risk populations and blood donors in a referral hospital in the south of Brazil.Scientific reports · 2021Trial
- Trends and projections of hepatitis E incidence in Jiangsu Province of eastern China from 2007 to 2021: An analysis based on age-period-cohort models.Infectious Disease Modelling · 2025Article
- Dynamic and Seasonal Distribution of Enteric Viruses in Surface and Well Water in Riyadh (Saudi Arabia).Pathogens (Basel, Switzerland) · 2023Article
- Treatment of Hepatitis E.Advances in experimental medicine and biology · 2023Article
- Seroprevalence of hepatitis A and hepatitis E in patients at a teaching hospital of northern India over a period of 8 years.Journal of family medicine and primary care · 2022Article
- Prevalence of hepatitis E virus in children with acute hepatitis: one Egyptian center study.Germs · 2020Article
- Prevalence of anti-hepatitis E virus IgG antibodies in sera from hemodialysis patients in Tripoli, Lebanon.PloS one · 2020Article
- Prevalence of hepatitis E virus in thalassemia patients with hepatitis C in Tehran, Iran.Iranian journal of microbiology · 2019Article
- Waterborne & foodborne viral hepatitis: A public health perspective.The Indian journal of medical research · 2019Article
- Hepatitis E in pigs in Israel: seroprevalence, molecular characterisation and potential impact on humans.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- Hepatitis E in High-Income Countries: What Do We Know? And What Are the Knowledge Gaps?Viruses · 2018Review
- Article
- Hepatitis E: A Literature Review.Journal of clinical and translational hepatology · 2017Review
- Phage-displayed peptides that mimic epitopes of hepatitis E virus capsid.Medical microbiology and immunology · 2017Article
- Epidemiology of Hepatitis E in Pregnant Women and Children in Iran: A General Overview.Journal of clinical and translational hepatology · 2016Review
- Epidemiology of hepatitis E virus in Iran.World journal of gastroenterology · 2016Review
- Identification of Distribution Characteristics and Epidemic Trends of Hepatitis E in Zhejiang Province, China from 2007 to 2012.Scientific reports · 2016Article
- The Honolulu Liver Disease Cluster at the Medical Center: Its Mysteries and Challenges.International journal of molecular sciences · 2016Review
- Article
- Hepatitis E: An Underdiagnosed, Emerging Infection in Nonendemic Regions.Journal of clinical and translational hepatology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mysterious aspects of the long presumed to be well-known hepatitis E virus (HEV) have recently surfaced that distinguish it from other hepatotropic viruses. It is a cause of chronic hepatitis in immunosuppressed patients. It has human to human transmission through blood and mantains high seroprevalence in blood donors. HEV has also been found to occur more frequently in the West in those without a history of travel to endemic countries. It has varied extrahepatic manifestations and has multiple non-human reservoirs including pigs and rats. Considering these recent discoveries, it appears odd that HEV is not sought more frequently when working up acute and chronic hepatitis patients. The disease is particularly severe among pregnant women and has a high attack rate in young adults. What adds to its ambiguity is the absence of a well-established diagnostic criteria for its detection and that there is no specific antiviral drug for hepatitis E, except for isolated cases where ribavirin or pegylated interferon alpha has been used with occasional success. This review paper discusses the recent advances in the knowledge of the virus itself, its epidemiology, diagnostic approach and prevention, and the treatment options available.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.