Evidence map›Paper›PMID 25691821›Full record

ReviewContemporary oncology (Poznan, Poland)2015

Biology of renal tumour cancer stem cells applied in medicine.

Damian Matak, Lukasz Szymanski, Cezary Szczylik, Rafal Sledziewski, Fei Lian, Ewa Bartnik, Anna Sobocinska, Anna M Czarnecka

Open access · goldAbstract readReview
In one paragraph

Review in Contemporary oncology (Poznan, Poland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Damian MatakDepartment of Oncology with Laboratory of Molecular Oncology, Military Institute of Medicine, Warsaw, Poland ; School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland ; Authors contributed equally to the work.
Lukasz SzymanskiDepartment of Oncology with Laboratory of Molecular Oncology, Military Institute of Medicine, Warsaw, Poland ; Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Poland ; Authors contributed equally to the work.
Cezary SzczylikDepartment of Oncology with Laboratory of Molecular Oncology, Military Institute of Medicine, Warsaw, Poland.
Rafal SledziewskiDepartment of Oncology with Laboratory of Molecular Oncology, Military Institute of Medicine, Warsaw, Poland.
Fei LianEmory School of Medicine Atlanta, GA, USA.
Ewa BartnikInstitute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Poland ; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Anna SobocinskaDepartment of Oncology with Laboratory of Molecular Oncology, Military Institute of Medicine, Warsaw, Poland ; Faculty of Biology, University of Warsaw, Poland.
Anna M CzarneckaDepartment of Oncology with Laboratory of Molecular Oncology, Military Institute of Medicine, Warsaw, Poland.
Emory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present article highlights the diverse role of stem cells in normal kidney and renal cancer, with special emphasis on surface markers. Proteins such as CD105 and CD133 have been reported as being significant in clear cell renal cell carcinoma (ccRCC) cancer stem cells. The role of normal kidney progenitor cells and their surface markers is compared with the role of those surface markers in ccRCC. Subsequently, we state the current hypothesis about origin of tumour-initiating cells along with their clinical and prognostic potential in RCC. Finally, we present future perspectives with respect to recent studies.

Indexed as

cancer stem cellsrenal cancertumour-initiating cells

Identifiers

PMID25691821
PMCPMC4322535
OpenAlexW2183212613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.