ArticleSocial cognitive and affective neuroscience2015
White matter microstructure in the executive network associated with aggression in healthy adolescents and young adults.
Article in Social cognitive and affective neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- White-matter tract abnormalities and antisocial behavior: A systematic review of diffusion tensor imaging studies across development.NeuroImage. Clinical · 2017Pooled it
- White matter disconnection in acquired criminality.Molecular psychiatry · 2025Article
- White Matter Correlates of Psychopathic Traits in a Japanese Community Sample: Sex Matters!The European journal of neuroscience · 2025Article
- Neuroanatomical correlates of aggressiveness: a case-control voxel- and surface-based morphometric study.Brain structure & function · 2024Article
- Abnormalities in electroencephalographic microstates among violent patients with schizophrenia.Frontiers in psychiatry · 2023Article
- Effects of childhood trauma on aggressive behaviors and hippocampal function: the modulation of COMT haplotypes.Psychoradiology · 2023Article
- Lead exposure and antisocial behavior: A systematic review protocol.Environment international · 2022Article
- Abnormal neurite density and orientation dispersion in frontal lobe link to elevated hyperactive/impulsive behaviours in young adults with traumatic brain injury.Brain communications · 2022Article
- Regions of white matter abnormalities in the arcuate fasciculus in veterans with anger and aggression problems.Brain structure & function · 2020Article
- History of childhood maltreatment is associated with reduced fractional anisotropy of the accumbofrontal 'reward' tract in healthy adults.Brain imaging and behavior · 2020Article
- Functional Activation During a Cognitive Control Task in Healthy Youth Specific to Externalizing or Internalizing Behaviors.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
- Neural Networks Mediating High-Level Mentalizing in Patients With Right Cerebral Hemispheric Gliomas.Frontiers in behavioral neuroscience · 2018Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Predicting which individuals may engage in aggressive behavior is of interest in today's society; however, there is little data on the neural basis of aggression in healthy individuals. Here, we tested whether regional differences in white matter (WM) microstructure were associated with later reports of aggressive tendencies. We recontacted healthy young adults an average of 3 years after they underwent research MRI scans. Via electronic survey, we administered the Buss Perry Aggression Questionnaire. We divided aggression into Aggressive Thoughts (Anger and Hostility subscales) and Aggressive Acts (Verbal and Physical subscales) and used Tract-Based Spatial Statistics to test the relationship of those measures to WM microstructure. In 45 individuals age 15-30 at baseline, we observed significant relationships between Aggressive Acts and fractional anisotropy (FA) in a parietal region consistent with the superior longitudinal fasciculus (SLF). As the SLF has an established relationship to executive function, we performed an exploratory analysis in a subset of individuals with working memory data. Decreased FA in executive network regions, as well as working memory performance, were associated with later self-reported aggressive tendencies. This has implications for our healthy behavior understanding of as well as that of patient populations known to have executive dysfunction.
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