Evidence map›Paper›PMID 25691775›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2015

Ang1 and Tie2 are predictive biomarkers for bevacizumab-letter.

Joseph Ciccolini, Cindy Serdjebi, Dominique Barbolosi, Bruno Lacarelle, Fabrice Barlesi

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04770376 (Prospective Pilot Study for the Evaluation of the Predictive Value of Blood Levels of Angiopoietin 1), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04770376 unknown statusnot on this mapstarted 2020, after this paper: background citation

Prospective Pilot Study for the Evaluation of the Predictive Value of Blood Levels of Angiopoietin 1 (ANG1) and Endothelial Internal Tunica Cell Kinase 2 (TiE2) in Patients With Ovarian Cancer Treated With Chemotherapy Associated to bevAcizumab

TypeobservationalSponsorIRCCS Azienda Ospedaliero-Universitaria di BolognaRan2020 to 2023Enrolled150ConditionsOvarian CancerArmsObservational study. Blood samples will be collected at scheduled blood draws performed as per clinical practice before each cycle of chemotherapy.
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Joseph CiccoliniAix Marseille University, Assistance Publique Hôpitaux de Marseille, Laboratoire de Pharmacocinétique Clinique, Marseille, France. Aix Marseille University, Simulation and Modelling, Adaptive Response for Therapeutics in Cancer (SMARTc), Inserm U911 CRO2, Marseille, France. joseph.ciccolini@univ-amu.fr.
Cindy SerdjebiAix Marseille University, Assistance Publique Hôpitaux de Marseille, Laboratoire de Pharmacocinétique Clinique, Marseille, France. Aix Marseille University, Simulation and Modelling, Adaptive Response for Therapeutics in Cancer (SMARTc), Inserm U911 CRO2, Marseille, France.
Dominique BarbolosiAix Marseille University, Simulation and Modelling, Adaptive Response for Therapeutics in Cancer (SMARTc), Inserm U911 CRO2, Marseille, France.
Bruno LacarelleAix Marseille University, Assistance Publique Hôpitaux de Marseille, Laboratoire de Pharmacocinétique Clinique, Marseille, France. Aix Marseille University, Simulation and Modelling, Adaptive Response for Therapeutics in Cancer (SMARTc), Inserm U911 CRO2, Marseille, France.
Fabrice BarlesiAix Marseille University, Simulation and Modelling, Adaptive Response for Therapeutics in Cancer (SMARTc), Inserm U911 CRO2, Marseille, France. Aix Marseille University, Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology and Therapeutic Innovations Department, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiopoietin-1Antibodies, Monoclonal, HumanizedFemaleHumansOvarian NeoplasmsReceptor, TIE-2Angiopoietin-1Antibodies, Monoclonal, HumanizedReceptor, TIE-2

Identifiers

PMID25691775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.