Evidence map›Paper›PMID 25691683›Full record

ArticleCirculation. Cardiovascular genetics2015

Somatic mutations and atrial fibrillation: the end or just the beginning?

Steven A Lubitz, Patrick T Ellinor

Abstract readEditorialComment
In one paragraph

Article in Circulation. Cardiovascular genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Steven A LubitzFrom the Division of Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston; and Medical and Population Genetics Program, The Broad Institute, Cambridge, MA.
Patrick T EllinorFrom the Division of Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston; and Medical and Population Genetics Program, The Broad Institute, Cambridge, MA. ellinor@mgh.harvard.edu.

Funding

PHARMACOGENOMICS OF ARRHYTHMIA THERAPYU01HL065962 · NHLBI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2001 to 2009
$24.8M
IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
Pharmacogenomics of Arrhythmia TherapyU19HL065962 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RODEN, DAN M · 2010 to 2014
$17.4M
Determining the Role of the Potassium Channel, KCNN3, in Atrial FibrillationR01HL104156 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2010 to 2013
$2.1M
Mentoring in Arrhythmia ResearchK24HL105780 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2011 to 2020
$1.2M
Atrial Fibrillation: Bridging genetic discovery and clinical associationsK23HL114724 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LUBITZ, STEVEN A · 2013 to 2017
$893k
Doris Duke Charitable Foundation 2014105NHLBI NIH HHS 1K24HL105780NHLBI NIH HHS 1R01HL104156NHLBI NIH HHS 2R01HL092577NHLBI NIH HHS HL065962NHLBI NIH HHS K23 HL114724NHLBI NIH HHS K23HL114724NHLBI NIH HHS K24 HL105780NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL104156NHLBI NIH HHS U01 HL065962NHLBI NIH HHS U19 HL065962
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

High-Throughput Nucleotide SequencingMosaicismMutation, MissenseAtrial FibrillationFemaleHumansMaleatrial fibrillationEditorialsgenesgeneticsmutation

Identifiers

PMID25691683
PMCPMC4405795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.