Evidence map›Paper›PMID 25691277›Full record

ArticleAnnals of surgical oncology2015

Optimal Treatment Strategy in Rectal Cancer Surgery: Should We Be Cowboys or Chickens?

Heleen S Snijders, Nicoline J van Leersum, Daan Henneman, Alexander C de Vries, Rob A E M Tollenaar, Anne M Stiggelbout, Michel W J M Wouters, Jan Willem T Dekker

Open access · hybridAbstract read
In one paragraph

Article in Annals of surgical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
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  5. Review
  6. Article
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  8. Article
  9. Article
  10. The Selective Use of a Diverting Stoma in Rectal Surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
  11. Article
  12. Article
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  15. Article
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  18. A multicentre cohort study of serum and peritoneal biomarkers to predict anastomotic leakage after rectal cancer resection.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2020
    Article
  19. Article
  20. Transanal total mesorectal excision: how are we doing so far?Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Heleen S SnijdersDepartment of Surgery, Leiden University Medical Centre, Leiden, The Netherlands. h.s.snijders@lumc.nl.
Nicoline J van LeersumDepartment of Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
Daan HennemanDepartment of Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
Alexander C de VriesDepartment of Surgery, Medical Center Haaglanden, The Hague, The Netherlands.
Rob A E M TollenaarDepartment of Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
Anne M StiggelboutDepartment of Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands.
Michel W J M WoutersDepartment of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Jan Willem T DekkerDepartment of Surgery, Reinier de Graaf Gasthuis, Delft, The Netherlands.
Leiden University Medical Center · NLLeiden University · NLMedisch Centrum Haaglanden · NLReinier de Graaf Hospital · NLThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSurgeons and hospitals are increasingly accountable for their postoperative complication rates, which may lead to risk adverse treatment strategies in rectal cancer surgery. It is not known whether a risk adverse strategy leads to providing better care. In this study, the association between the strategy of hospitals regarding defunctioning stoma construction and postoperative outcomes in rectal cancer treatment was evaluated.

methodsPopulation-based data of the Dutch Surgical Colorectal Audit, including 3,104 patients undergoing rectal cancer resection between January 2009 and July 2012 in 92 hospitals, were used. Hospital variation in (case-mix-adjusted) defunctioning stoma rates was calculated. Anastomotic leakage and 30-day mortality rates were compared in hospitals with a high and low tendency towards stoma construction.

resultsOf all patients, 76 % received a defunctioning stoma; 9.6 % of all patients developed anastomotic leakage. Overall postoperative mortality rate was 1.8 %. The hospitals' adjusted proportion of defunctioning stomas varied from 0 to 100 %, and there was no significant correlation between the hospitals' adjusted stoma and anastomotic leakage rate. Severe anastomotic leakage was similar (7.0 vs. 7.1 %; p = 0.95) in hospitals with the lowest and highest stoma rates. Mild leakage and postoperative mortality rates were higher in hospitals with high stoma rates.

conclusionsA high tendency towards stoma construction in rectal cancer surgery did not result in lower overall anastomotic leakage or mortality rates. It seems that the ability to select patients for stoma construction is the key towards preferable outcomes, not a risk adverse strategy.

Indexed as

Quality of Health CareAdolescentAdultAgedAged, 80 and overAnastomotic LeakFemaleHospital AdministrationHospitalsHumansMaleMiddle AgedNetherlandsOrganizational PolicyOstomyRectal Neoplasms

Identifiers

PMID25691277
PMCPMC4565862
OpenAlexW1994632379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.