ArticleInternational orthopaedics2015
Post-traumatic thrombo-embolic complications in polytrauma patients.
Article in International orthopaedics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 52 citations in OpenAlex.
- Impact of whole-body vibration training on ankle joint proprioception and balance in stroke patients: a prospective cohort study.BMC musculoskeletal disorders · 2024Trial
- Association Between Preoperative Calcium Levels and the Occurrence of Postoperative PE in Trauma Patients: A Retrospective Multicenter Cohort Study.World journal of surgery · 2026Article
- Tranexamic acid in multiply injured patients-the independent risk of thromboembolic complications with repeated dosing: retrospective analysis based on the TraumaRegister DGU®.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Article
- Change in resuscitation influenced development and severity of inflammatory complications in severely injured.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- The Characteristics of Severely Injured Trauma Patients Admitted to a Level I Trauma Center with Pre-Injury Use of Oral Anticoagulation (OAC) or Antiplatelet Therapy (APT).Journal of clinical medicine · 2025Article
- Insights into VTE risk in trauma patients: an observational study in an Irish trauma patient population.Irish journal of medical science · 2025Observational
- Establishment and validation of a predictive model for lower extremity deep vein thrombosis in patients with traumatic pelvic fractures.Thrombosis journal · 2024Article
- Sex-Based Differences in Polytraumatized Patients between 1995 and 2020: Experiences from a Level I Trauma Center.Journal of clinical medicine · 2024Article
- Factors Associated with Venous Thromboembolism Development in Patients with Traumatic Brain Injury.Neurocritical care · 2024Article
- Pulmonary embolism following severe polytrauma: a retrospective study from a level I trauma center in China.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Venous Thrombus Embolism in Polytrauma: Special Attention to Patients with Traumatic Brain Injury.Journal of clinical medicine · 2023Article
- Haemostasis and Inflammatory Parameters as Potential Diagnostic Biomarkers for VTE in Trauma-Immobilized Patients.Diagnostics (Basel, Switzerland) · 2023Review
- Review
- Clinical Characteristics and Risk Factors for Early versus Late Pulmonary Embolism in Trauma Patients: A Retrospective, Observational Study.International journal of general medicine · 2022Article
- A nested case-control study of risk for pulmonary embolism in the general trauma population using nationwide trauma registry data in Japan.Scientific reports · 2021Article
- Thromboembolic complications among multiple injured patients with pelvic injuries: identifying risk factors for possible patient-tailored prophylaxis.World journal of emergency surgery : WJES · 2021Article
- Clinical Study on the Screening of Lower Extremity Deep Venous Thrombosis by D-Dimer Combined with RAPT Score Among Orthopedic Trauma Patients.Indian journal of orthopaedics · 2020Article
- Post-traumatic pulmonary embolism: incidence, physiopathology, risk factors of early occurrence, and impact outcome. A narrative review.American journal of cardiovascular disease · 2020Review
- Early post-traumatic pulmonary embolism in intensive care unit: incidence, risks factors, and impact outcome.American journal of cardiovascular disease · 2020Article
- Early post-traumatic pulmonary-embolism in patients requiring ICU admission: more complicated than we think!Journal of thoracic disease · 2018Article
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThrombo-embolic events after trauma are considered to be life-threatening complications. Our aim was to determine the incidence of arterial and venous thrombo-embolic events (TE) in severely-injured trauma patients, and its associated risk factors by using a large trauma registry.
methodsPatients' data from the TraumaRegister DGU® (TR-DGU) were screened for TE (DVT [symptomatic deep vein thrombosis], PE [symptomatic pulmonary embolism], MI [myocardial infarction], and stroke) through the clinical course of severely injured adult trauma patients from January 2005 to December 2012. Univariate analysis was used to compare the clinical outcomes (endpoints: mortality, ICU and hospital length of stay, ventilator days), and a multivariate regression analysis was used to assess the independent risk factors associated with each TE event.
resultsFrom a cohort of 40,846 trauma patients, 1122 (2.8%) patients developed a TE during their post-traumatic clinical course (313, 0.8% DVT; 425, 1.0% PE; 160, 0.4% MI and 231, 0.6% stroke). ICU length of stay [LOS], total LOS, days on mechanical ventilation, and incidence of multiple organ failure (MOF) and sepsis were significantly increased in patients with TE complications. Injury severity, major pelvic injury, and one or more operations were found to be independent risk factors for the development of DVT. Age ≥ 60 years, male gender, and more than one operation were risk factors for PE development. For MI age was the only significant risk factor. The occurrence of a stroke is increased in patients with an age ≥ 60 years, major head injury (AIS head ≥ 3), and more than one operation. Finally, mortality rates were significantly higher in the TE group when compared to the non-TE cohort (21.8% vs. 12.7%; p < 0.001).
conclusionTE complications were associated with longer ICU and hospital stay as well as a higher mortality. Overall, age and repeated operations were the most important risk factors for the development of TE events.
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