Evidence map›Paper›PMID 25690841›Full record

ArticleEpidemiology and infection2015

Environmental predictors of diarrhoeal infection for rural and urban communities in south India in children and adults.

D Kattula, M R Francis, A Kulinkina, R Sarkar, V R Mohan, S Babji, H D Ward, G Kang, V Balraj, E N Naumova

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

D KattulaDivision Gastrointestinal Sciences,Christian Medical College,Vellore,India.
M R FrancisDivision Gastrointestinal Sciences,Christian Medical College,Vellore,India.
A KulinkinaDepartment of Civil and Environmental Engineering,Tufts University School of Engineering,Medford,MA,USA.
R SarkarDivision Gastrointestinal Sciences,Christian Medical College,Vellore,India.
V R MohanDepartment of Community Health,Christian Medical College,Vellore,India.
S BabjiDivision Gastrointestinal Sciences,Christian Medical College,Vellore,India.
H D WardDivision Gastrointestinal Sciences,Christian Medical College,Vellore,India.
G KangDivision Gastrointestinal Sciences,Christian Medical College,Vellore,India.
V BalrajDepartment of Community Health,Christian Medical College,Vellore,India.
E N NaumovaDivision Gastrointestinal Sciences,Christian Medical College,Vellore,India.
Christian Medical College & Hospital · INTufts University · USTufts Medical Center · US

Funding

Infectious Disease Training-Pathogenesis/Host ResponseT32AI007329 · NIAID · TUFTS MEDICAL CENTER · PI HU, LINDEN T · 1988 to 2018
$4.1M
Multi-disciplinary research training in enteric infectionsD43TW007392 · FIC · CHRISTIAN MEDICAL COLLEGE · PI KANG, GAGANDEEP · 2005 to 2020
$2.9M
Tufts-CMC Framework Program for Global Health InnovationD43TW009377 · FIC · TUFTS UNIVERSITY BOSTON · PI KANG, GAGANDEEP, WANKE, CHRISTINE A · 2013 to 2017
$1.6M
FIC NIH HHS D43TW0007392FIC NIH HHS D43 TW007392FIC NIH HHS D43 TW009377Wellcome Trust
6 · The paper itself

Abstract

Diarrhoeal diseases are major causes of morbidity and mortality in developing countries. This longitudinal study aimed to identify controllable environmental drivers of intestinal infections amidst a highly contaminated drinking water supply in urban slums and villages of Vellore, Tamil Nadu in southern India. Three hundred households with children (<5 years) residing in two semi-urban slums and three villages were visited weekly for 12-18 months to monitor gastrointestinal morbidity. Households were surveyed at baseline to obtain information on environmental and behavioural factors relevant to diarrhoea. There were 258 diarrhoeal episodes during the follow-up period, resulting in an overall incidence rate of 0·12 episodes/person-year. Incidence and longitudinal prevalence rates of diarrhoea were twofold higher in the slums compared to rural communities (P < 0·0002). Regardless of study site, diarrhoeal incidence was highest in infants (<1 year) at 1·07 episodes/person-year, and decreased gradually with increasing age. Increasing diarrhoeal rates were associated with presence of children (<5 years), domesticated animals and low socioeconomic status. In rural communities, open-field defecation was associated with diarrhoea in young children. This study demonstrates the contribution of site-specific environmental and behavioural factors in influencing endemic rates of urban and rural diarrhoea in a region with highly contaminated drinking water.

Indexed as

AdolescentAdultAgedChildChild, PreschoolDiarrheaEnvironmental ExposureFemaleHumansIncidenceIndiaInfantInfant, NewbornLongitudinal StudiesMaleMiddle AgedDiarrhoeaincidence raterisk factorsruralurban

Identifiers

PMID25690841
PMCPMC9151025
OpenAlexW2071190632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.