Trial reportClinical oral investigations2015
Evaluation of salivary mucins in children with deciduous and mixed dentition: comparative analysis between high and low caries-risk groups.
Trial report in Clinical oral investigations, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Association of salivary proteins with dental caries in children with mixed dentition: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Pooled it
- Exploring the Correlation between Salivary Spinnbarkeit and Caries Scores.Caries research · 2024Article
- Caries Management-The Role of Surface Interactions in De- and Remineralization-Processes.Journal of clinical medicine · 2022Review
- Analysis of salivary proteomic biomarkers for the surveillance of changes in high-risk status of early childhood caries.BMC oral health · 2021Article
- Downregulation of Salivary Proteins, Protective against Dental Caries, in Type 1 Diabetes.Proteomes · 2021Article
- Salivary Protein Roles in Oral Health and as Predictors of Caries Risk.Open life sciences · 2018Article
- Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment.International journal of oral science · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to examine levels of salivary mucins in children with deciduous and mixed dentition and to determine correlations between salivary mucins and dental caries status in two dentition stages. MATERIALS AND
methodsSaliva samples were collected from preschool children with deciduous dentition aged between 4 and 6 years (n = 60) and school children with mixed dentition aged between 9 and 11 years (n = 60). In each age group, the subjects were divided into two categories: high and low caries risk (n = 30 each). Salivary mucins (MUC5B and MUC7) were measured by enzyme-linked immunosorbent assay (ELISA).
resultsThere were no significant differences in MUC5B and MUC7 levels between high and low caries-risk groups in preschool children. Significantly increased MUC5B (p = 0.01) and decreased MUC7 (p = 0.04) levels in a low caries-risk group were demonstrated in school children. No significant correlations were observed between salivary mucins and dental caries in preschool children, whereas a significantly negative correlation (r = -0.29, p = 0.03) between MUC5B and the number of decayed teeth was observed in school children.
conclusionPatterns of salivary mucin expression in relation to dental caries were different between preschool and school children. The present findings suggest that changes in oral environment from deciduous to mixed dentition may affect the secretion of salivary mucins in response to dental caries. CLINICAL RELEVANCE: The present study provides additional information that changes in oral environment from deciduous to mixed dentition stage possibly affect the secretion of salivary mucins in response to dental caries.
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