Evidence map›Paper›PMID 25689743›Full record

Trial reportNutrients2015

Effects of two dietary fibers as part of ready-to-eat cereal (RTEC) breakfasts on perceived appetite and gut hormones in overweight women.

David W Lafond, Kathryn A Greaves, Kevin C Maki, Heather J Leidy, Dale R Romsos

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 7 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

David W LafondKellogg Company, WKKI 2 Hamblin Ave E, Battle Creek, MI 49017, USA. david.lafond@kellogg.com.
Kathryn A GreavesKellogg Company, WKKI 2 Hamblin Ave E, Battle Creek, MI 49017, USA. kathy.greaves@kellogg.com.
Kevin C MakiBiofortis Clinical Research/Midwest Center for Metabolic & Cardiovascular Research, 489 Taft Avenue, Glen Ellyn, IL 60137, USA. kmaki@mc-mcr.com.
Heather J LeidyDepartment of Nutrition & Exercise Physiology, University of Missouri, 307 Gwynn Hall, Columbia, MO 65211, USA. leidyh@health.missouri.edu.
Dale R RomsosDepartment of Food Science and Human Nutrition, Michigan State University, 469 Wilson Road, East Lansing, MI 48824-1224, USA. dromsos@msu.edu.
Kellogg's (United States) · USMB Clinical Research and Consulting (United States) · USMichigan State University · USUniversity of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of an enzyme-hydrolyzed arabinoxylan from wheat (AXOS) versus an intact arabinoxylan from flax (FLAX) added to a ready-to-eat cereal (RTEC) on the postprandial appetitive, hormonal, and metabolic responses in overweight women (BMI 25.0-29.9 kg/m2) were evaluated. Subsequent meal energy intake was also assessed. Two randomized, double-blind, crossover design studies were completed. For trial 1, the participants consumed the following RTEC breakfast, matched for total weight and varied in energy content: low-fiber (LF, 4 g); high-fiber (HF, 15 g) as either AXOS or FLAX. For trial 2, the participants consumed LF, HF-AXOS, and HF-FLAX RTECs but also consumed another LF breakfast that was isocaloric (LF-iso) to that of the HF breakfasts. Perceived appetite and blood samples (trial 2 only) were assessed before and after breakfast. An ad libitum lunch was offered 4 h post-breakfast. No differences in postprandial appetite responses were observed among any breakfasts in either trial. The HF-AXOS and HF-FLAX led to increased postprandial GLP-1 and peptide YY (PYY) concentrations vs. LF-iso. No differences were observed in lunch meal energy intake among breakfast meals in either trial. Collectively, these data suggest that 15 g of low molecular weight fiber added to RTECs did not affect perceived appetite or subsequent energy intake despite differences in satiety hormone signaling in overweight females.

Indexed as

AppetiteBreakfastEdible GrainAdolescentAdultBody Mass IndexCase-Control StudiesCross-Over StudiesDietary FiberDouble-Blind MethodEnergy IntakeFemaleFlaxGastrointestinal HormonesGlucagon-Like Peptide 1HumansDietary FiberGastrointestinal HormonesGlucagon-Like Peptide 1Peptide YY

Identifiers

PMID25689743
PMCPMC4344586
OpenAlexW2052789273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.