Evidence map›Paper›PMID 25688605›Full record

Trial reportJournal of the American Geriatrics Society2015

Use of atypical antipsychotics in nursing homes and pharmaceutical marketing.

Camilla B Pimentel, Jennifer L Donovan, Terry S Field, Jerry H Gurwitz, Leslie R Harrold, Abir O Kanaan, Celeste A Lemay, Kathleen M Mazor, Jennifer Tjia, Becky A Briesacher

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03692182 (Antipsychotic Use Within the Program of All-inclusive Care for the Elderly), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03692182 completednot on this mapstarted 2017, after this paper: background citation

Antipsychotic Use Within the Program of All-inclusive Care for the Elderly (PACE)

TypeobservationalSponsorTabula Rasa HealthCareRan2017 to 2019Enrolled10,000ConditionsBehavioral and Psychiatric Symptoms of Dementia
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Marketing Antipsychotics to Correctional Facilities: A Review of Pharmaceutical Industry Documents.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Camilla B PimentelClinical and Population Health Research Program, Graduate School of Biomedical Sciences, University of Massachusetts Medical School, Worcester, Massachusetts.
Jennifer L Donovan
Terry S Field
Jerry H Gurwitz
Leslie R Harrold
Abir O Kanaan
Celeste A Lemay
Kathleen M Mazor
Jennifer Tjia
Becky A Briesacher
MCPHS University · USUniversity of Massachusetts Chan Medical School · US

Funding

iADAPT: Off-Label Use of Antipsychotics in the Nursing HomeR18HS019351 · AHRQ · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GURWITZ, JERRY H · 2010 to 2010
$1.5M
Cost-related Underuse of Medications and the Health of Older AdultsK01AG031836 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BRIESACHER, BECKY A · 2008 to 2012
$679k
Assessing and Improving Arthritis Medication Adherence: Gout as a ModelK23AR053856 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HARROLD, LESLIE R · 2007 to 2011
$641k
AHRQ HHS R18 HS019351AHRQ HHS R18HS019351NIAMS NIH HHS K23 AR053856NIAMS NIH HHS K23AR053856NIA NIH HHS K01 AG031836NIA NIH HHS K01AG031836
6 · The paper itself

Abstract

objectivesTo describe the current extent and type of pharmaceutical marketing in nursing homes (NHs) in one state and to provide preliminary evidence for the potential influence of pharmaceutical marketing on the use of atypical antipsychotics in NHs.

designNested mixed-methods, cross-sectional study of NHs in a cluster randomized trial.

settingForty-one NHs in Connecticut.

participantsNH administrators, directors of nursing, and medical directors (n = 93, response rate 75.6%). MEASUREMENTS: Quantitative data, including prescription drug dispensing data (September 2009-August 2010) linked with Nursing Home Compare data (April 2011), were used to determine facility-level prevalence of atypical antipsychotic use, facility-level characteristics, NH staffing, and NH quality. Qualitative data, including semistructured interviews and surveys of NH leaders conducted in the first quarter of 2011, were used to determine encounters with pharmaceutical marketing.

resultsLeadership at 46.3% of NHs (n = 19) reported pharmaceutical marketing encounters, consisting of educational training, written and Internet-based materials, and sponsored training. No association was detected between level of atypical antipsychotic prescribing and reports of any pharmaceutical marketing by at least one NH leader.

conclusionNH leaders frequently encounter pharmaceutical marketing through a variety of ways, although the impact on atypical antipsychotic prescribing is unclear.

Indexed as

Marketing of Health ServicesNursing HomesQuality of Health CareAntipsychotic AgentsCluster AnalysisConnecticutCross-Sectional StudiesDrug UtilizationHealth Facility SizeHumansPractice Patterns, Physicians'Antipsychotic Agentsatypical antipsychoticsnursing homespharmaceutical marketing

Identifiers

PMID25688605
PMCPMC4332626
OpenAlexW2071936827

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.