ArticlePloS one2015
The dynamic distribution of porcine microbiota across different ages and gastrointestinal tract segments.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 240 papers, 1 of them a synthesis that pooled it.
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Who cites it
240 citing papers in PubMed, 1 synthesis or guideline pooled it, 414 citations in OpenAlex.
- Dynamic Distribution of Gut Microbiota in Pigs at Different Growth Stages: Composition and Contribution.Microbiology spectrum · 2022Pooled it
- Comparative Effects of Different Dietary Acidifiers on Growth Performance and Intestinal Health in Weaned Piglets.Animals : an open access journal from MDPI · 2026Article
- Microbiome modelling for post-mortem interval estimation across species and climates: swine analogues in a British summer and external validation in human donors from the USA.Scientific reports · 2026Article
- Global landscape of alternative polyadenylation during the growth and development of skeletal muscle in pigs.BMC genomics · 2026Article
- Metagenomic sequencing reveals high reproducibility of human donor microbiota transplanted into germ-free mice via lower gut route.Journal of Zhejiang University. Science. B · 2026Article
- Weaning Influences Epithelial Morphology, Gene Expression and Gut Microbiota Composition in Piglets.Animals : an open access journal from MDPI · 2026Article
- Composition and nutritional role of gut microbiota on growth performance of pigs at different growth stages.The British journal of nutrition · 2026Article
- The developmental trajectory and maturation of the Hulunbuir sheep (Ovis aries) microbiome.Animal microbiome · 2026Article
- From predisposition to recovery: field evidence of interactions between the gut microbiota and Brachyspira hyodysenteriae infection.Veterinary research · 2026Article
- Age influences serum immune indices and gut microbiota composition in adult broilers.Frontiers in microbiology · 2026Article
- Gut microbiota regulates growth retardation in pigs through their metabolites of taurine and butyric acids.Frontiers in microbiology · 2026Article
- Dynamic picture of the pig gut's microbiota under normal and pathological conditions.Animal microbiome · 2025Article
- Sex-Specific Differences in Gut Microbial Composition and Metabolism of Jiangshan Black Pigs.Microorganisms · 2025Article
- Integrated 16S rDNA and Metabolomics Analysis Unveils Dietary Fiber-Induced Changes in Small Intestinal Microbiota and Metabolites of Pigs.Veterinary sciences · 2025Article
- Rethinking the fight against pig-related human salmonellosis in the European union.Porcine health management · 2025Review
- Severity of Brachyspira hyodysenteriae colitis correlates to the changes observed in the microbiota composition and its associated functionality in the large intestine.Animal microbiome · 2025Article
- Integrating Machine Learning to Identify Key Microbiota of Gut Community Changes Across Different Stages in Dahe Black Pigs.Microorganisms · 2025Article
- Influence of Different Litter Regimens on Ceca Microbiota Profiles inAnimals : an open access journal from MDPI · 2025Article
- Differences in rectal fecal microbes among Hu sheep, Tibetan sheep, and their hybrid breeds and their relationship with growth traits.Microbiology spectrum · 2025Article
- Lactation performance and fecal microbiome of sows supplemented with antioxidant-rich polyherbal extract.Tropical animal health and production · 2025Article
180 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metagenome of gut microbes has been implicated in metabolism, immunity, and health maintenance of its host. However, in most of previous studies, the microbiota was sampled from feces instead of gastrointestinal (GI) tract. In this study, we compared the microbial populations from feces at four different developmental stages and contents of four intestinal segments at maturity to examine the dynamic shift of microbiota in pigs and investigated whether adult porcine fecal samples could be used to represent samples of the GI tract. Analysis results revealed that the ratio of Firmicutes to Bacteroidetes from the feces of the older pigs (2-, 3-, 6- month) were 10 times higher compared to those from piglets (1-month). As the pigs matured, so did it seem that the composition of microbiome became more stable in feces. In adult pigs, there were significant differences in microbial profiles between the contents of the small intestine and large intestine. The dominant genera in the small intestine belonged to aerobe or facultative anaerobe categories, whereas the main genera in the large intestine were all anaerobes. Compared to the GI tract, the composition of microbiome was quite different in feces. The microbial profile in large intestine was more similar to feces than those in the small intestine, with the similarity of 0.75 and 0.38 on average, respectively. Microbial functions, predicted by metagenome profiles, showed the enrichment associated with metabolism pathway and metabolic disease in large intestine and feces while higher abundance of infectious disease, immune function disease, and cancer in small intestine. Fecal microbes also showed enriched function in metabolic pathways compared to microbes from pooled gut contents. Our study extended the understanding of dynamic shift of gut microbes during pig growth and also characterized the profiles of bacterial communities across GI tracts of mature pigs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.