Evidence map›Paper›PMID 25688384›Full record

ArticleChemical communications (Cambridge, England)2015

Micropatterned, clickable culture substrates enable in situ spatiotemporal control of human PSC-derived neural tissue morphology.

G T Knight, J Sha, R S Ashton

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Clickable Biomaterials for Modulating Neuroinflammation.International journal of molecular sciences · 2022
    Review
  2. Review
  3. Bioengineering the human spinal cord.Frontiers in cell and developmental biology · 2022
    Review
  4. Review
  5. Brain Organoids as Model Systems for Genetic Neurodevelopmental Disorders.Frontiers in cell and developmental biology · 2020
    Review
  6. Engineered materials for organoid systems.Nature reviews. Materials · 2019
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

G T KnightDepartment of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA. rashton2@wisc.edu.
J Sha
R S Ashton

Funding

High-Throughput Modeling of ALS Using iPSC-Derived Neural Tube MicroarraysR21NS082618 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI ASHTON, RANDOLPH S · 2014 to 2015
$348k
NINDS NIH HHS 1R21NS082618-01A1NINDS NIH HHS R21 NS082618
6 · The paper itself

Abstract

We describe a modular culture platform that enables spatiotemporal control of the morphology of 2D neural tissues derived from human pluripotent stem cells (hPSCs) by simply adding clickable peptides to the media. It should be widely applicable for elucidating how spatiotemporal changes in morphology and substrate biochemistry regulate tissue morphogenesis.

Indexed as

Cell Culture TechniquesClick ChemistryHumansMolecular StructureNerve TissuePeptidesPluripotent Stem CellsPeptides

Identifiers

PMID25688384
PMCPMC4456773

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.